or MMR gene variants were mainly affected by brain tumours but also other solid tumours," says Professor Christian Kratz, initiator of the study published in the Journal of the National Cancer Institute [...] such a variant in a healthy child would currently not justify any immediate medical consequences," Professor Kratz emphasises. "Our results therefore give no reason to change the current practice of predictive [...] treating a child with cancer and the type of follow-up care after treatment has been completed," says Professor Kratz. "The detection of BRCA1/2 or MMR gene variants in an affected child with cancer also offers

diagnosed AML. This was the result of an international clinical study with the participation of Professor Dr. Michael Heuser, Senior Physician at the Department of Haematology, Haemostaseology, Oncology [...] compounds in the mouse model a few years ago and observed significant synergistic effects," says Professor Heuser. In the clinical trial, the researchers were now also able to demonstrate this effect in [...] for patients for whom intensive chemotherapy to fight the tumour is out of the question," says Professor Heuser. Another advantage is that undesirable side effects such as infections, pneumonia or blood

says Professor Claus. Next, the research team therefore wants to investigate an improved therapy and search for further molecular switches. SERVICE: For further information , please contact Professor Dr [...] still unclear how exactly the loss of motor neurones occurs. An international research team led by Professor Dr. Peter Claus, molecular biologist at the Institute of Neuroanatomy and Cell Biology at the Hannover [...] switch that is important for processing certain molecular signals in the motor nerve cells," says Professor Claus. The switch is called B-Raf and is a linchpin of the disease. "As the centre of an extensive

the stem cells come from a donor person, i.e. a relative or an anonymous person. Clinic Director Professor Dr. Arnold Ganser is pleased about the record: "We were able to help many affected people, although [...] are leukaemias, i.e. blood cancers, or lymphomas, i.e. tumours in the lymphatic tissue," explains Professor Dr Matthias Eder, Vice Clinic Director. Stem cell transplantation is indicated, for example, when [...] right time. "It could be that the person in question has Corona or is in quarantine," explains Professor Eder. "Then we would have conditioned the patient or the patient and the urgently needed donor stem

The Johann Georg Zimmermann Medal 2020 / 2021 will be awarded to Professor Dr. Konstanze Döhner and Professor Dr. Hartmut Döhner. Professor Konstanze Döhner has been Clinical Senior Physician and Head of [...] with regard to the reality of care for oncological patients. "Due to the special merits of Professor and Professor Döhner, we have decided this year to award the Johann Georg Zimmermann Medal jointly to two [...] Leukemias (AML) in the Department of Internal Medicine III at Ulm University Hospital since 2000. Professor Hartmut Döhner has been Medical Director of the Clinic for Internal Medicine III since 1999 and

MHH President Professor Dr. Michael P. Manns again personally presented the doctoral certificates to the doctoral candidates during a ceremony at the university. Together with Professor Dr. Frank Bengel [...] Bengel, Dean of Research at the university, Professor Dr. Siegfried Piepenbrock, Chairman of the Society of Friends of the MHH e.V., awarded the two doctoral prize winners: Christian Niehaus, MD, MHH Clinic [...] submitted his dissertation "Mucosal-associated invariant T cells in patients with liver cirrhosis" to Professor Markus Cornberg, MD, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology

benefit "treatment by a chief physician", you have the opportunity to be treated personally by Professor Dr. Schmelzle. In this case, your initial appointment will take place during the private consultation [...] accommodated in a single or double room in our modern transplant and private ward 85, if possible. Professor Schmelzle always performs his operations personally, assisted by his team of selected physicians [...] surgical treatment mission is more important than a patient's insurance status. For this reason, Professor Schmelzle and his team regularly treat patients who are not privately insured and who present to

neurodegenerative diseases such as Alzheimer's and frontotemporal dementia. A research team led by Professor Dr Evgeni Ponimaskin, a scientist at the MHH Institute of Neurophysiology , has already discovered [...] are increasingly found in brain regions that are affected in dementia. For the receptor 5-HT7R, Professor Ponimaskin has already found a high basal activity in previous studies. "This means that the receptor [...] potent inverse 5-HT7R receptor agonist," notes Dr Josephine Labus, who conducted this study with Professor Ponimaskin. It is true that dead nerve cells could not be repaired. However, in the early stages

to death within a few weeks. Already last year, an international study with the participation of Professor Dr. Michael Heuser, Senior Physician at the Department of Hematology, Hemostaseology, Oncology and [...] over four years. Combination therapy to inhibit cancer development In the earlier clinical trial, Professor Heuser, who also heads the Research Strategy and Translational Research department at the CCC Hannover [...] with IDH1-mutated AML who have already received ineffective pretreatment or have relapsed," says Professor Heuser. The first phase will determine the optimal dosage of molidustat. In the second phase, the

knowledge reaches those affected directly," says Professor Brigitte Schlegelberger, head of the FBREK Centre and the Institute of Human Genetics at the MHH. Professor Dr. Peter Hillemanns, Director of the Com [...] please contact Professor Brigitte Schlegelberger, Schlegelberger.Brigitte@mh-hannover.de , telephone (0511) 532-4522, or visit https://www.mhh.de/fbrek-zentrum . Centre Director Professor Dr. Brigitte