Prof. Dr. Jan Faix

Institute for Biophysical Chemistry, OE4350
Hannover Medical School
Carl-Neuberg-Straße 1
30625 Hannover

Office: Building I3, Floor 02, Room 1320    
Phone (office):     +49-511-532-2928
Phone (lab):        +49 511-532-5922
Fax:                     +49-511-532-5966
Email:                  faix.jan@mh-hannover.de

Research Focus:

The highly coordinated spatial and temporal control of the assembly and disassembly of actin filaments is a major determinant of vital cellular processes such as endocytosis, cytokinesis and cell migration. Specific protein assemblies, composed of various actin-binding proteins, operate in these processes to nucleate and elongate new actin filaments, arrange them into complex 3D arrays, and subsequently recycle them to replenish the G-actin pool. Accordingly, defects in the regulation of actin remodeling lead to various diseases including cancer as well as muscular, neurological and immunological disorders.