Publications by Prof. Dr. Reinhold Förster

2024

León-Lara X, Fichtner AS, Willers M, Yang T, Schaper K, Riemann L, Schöning J, Harms A, Almeida V, Schimrock A, Janssen A, Ospina-Quintero L, von Kaisenberg C, Förster R, Eberl M, Richter MF, Pirr S, Viemann D, Ravens S. γδ T cell profiling in a cohort of preterm infants reveals elevated frequencies of CD83+ γδ T cells in sepsis. J Exp Med. 2024 Jul 1;221(7):e20231987. doi: 10.1084/jem.20231987. Epub 2024 May 16. PMID: 38753245; PMCID: PMC11098939.

Odak I, Bayir LM, Riemann L, Sikora R, Schneider J, Xiao Y, Möhn N, Skripuletz T, Beutel G, Eder M, Ganser A, Förster R, Schultze-Florey CR, Koenecke C. Brief research report: in-depth immunophenotyping reveals stability of CD19 CAR T-cells over time. Front Immunol. 2024 Jan 22;15:1298598. doi: 10.3389/fimmu.2024.1298598. PMID: 38318174; PMCID: PMC10839090.

Odak I, Riemann L, Sandrock I, Cossmann A, Ramos GM, Hammerschmidt SI, Ritter C, Friedrichsen M, Hassan A, Dopfer-Jablonka A, Stankov MV, Weskamm LM, Addo MM, Ravens I, Willenzon S, Schimrock A, Ristenpart J, Janssen A, Barros-Martins J, Hansen G, Falk C, Behrens GMN, Förster R. Systems biology analysis reveals distinct molecular signatures associated with immune responsiveness to the BNT162b COVID-19 vaccine. EBioMedicine. 2024 Jan;99:104947. doi: 10.1016/j.ebiom.2023.104947. Epub 2023 Dec 30. PMID: 38160529; PMCID: PMC10792461.

2023

Stankov MV, Hoffmann M, Gutierrez Jauregui R, Cossmann A, Morillas Ramos G, Graalmann T, Winter EJ, Friedrichsen M, Ravens I, Ilievska T, Ristenpart J, Schimrock A, Willenzon S, Ahrenstorf G, Witte T, Förster R, Kempf A, Pöhlmann S, Hammerschmidt SI, Dopfer-Jablonka A, Behrens GMN. Humoral and cellular immune responses following BNT162b2 XBB.1.5 vaccination. Lancet Infect Dis. 2023 Nov 20:S1473-3099(23)00690-4. doi: 10.1016/S1473-3099(23)00690-4. Epub ahead of print. PMID: 37995739.

Yang, T., Barros-Martins, J., Wang, Z., Wencker, M., Zhang, J., Smout, J., Gambhir, P., Janssen, A., Schimrock, A., Georgiev, H., León-Lara, X., Weiss, S., Huehn, J., Prinz, I., Krueger, A., Foerster, R., Walzer, T., & Ravens, S. (2023). RORγt+ c-Maf+ Vγ4+ γδ T cells are generated in the adult thymus but do not reach the periphery. Cell reports, 42(10), 113230. https://doi.org/10.1016/j.celrep.2023.113230

Do, K. T. H., Willenzon, S., Ristenpart, J., Janssen, A., Volz, A., Sutter, G., Förster, R., & Bošnjak, B. (2023). The effect of Toll-like receptor agonists on the immunogenicity of MVA-SARS-2-S vaccine after intranasal administration in mice. Frontiers in cellular and infection microbiology, 13, 1259822. https://doi.org/10.3389/fcimb.2023.1259822

Barends, M., Koller, N., Schölz, C., Durán, V., Bošnjak, B., Becker, J., Döring, M., Blees, H., Förster, R., Kalinke, U., & Tampé, R. (2023). Dynamic interactome of the MHC I peptide loading complex in human dendritic cells. Proceedings of the National Academy of Sciences of the United States of America, 120(25), e2219790120. https://doi.org/10.1073/pnas.2219790120

Bošnjak, B., Henze, E., Lueder, Y., Do, K. T. H., Rezalotfi, A., Čuvalo, B., Ritter, C., Schimrock, A., Willenzon, S., Georgiev, H., Fritz, L., Galla, M., Wagner, K., Messerle, M., & Förster, R. (2023). MCK2-mediated MCMV infection of macrophages and virus dissemination to the salivary gland depends on MHC class I molecules. Cell reports, 42(6), 112597. Advance online publication. https://doi.org/10.1016/j.celrep.2023.112597

Barros-Martins, J., Hammerschmidt, S. I., Morillas Ramos, G., Cossmann, A., Hetzel, L., Odak, I., Köhler, M., Stankov, M. V., Ritter, C., Friedrichsen, M., Ravens, I., Schimrock, A., Ristenpart, J., Janssen, A., Willenzon, S., Bernhardt, G., Lichtinghagen, R., Bošnjak, B., Behrens, G. M. N., & Förster, R. (2023). Omicron infection-associated T- and B-cell immunity in antigen-naive and triple-COVID-19-vaccinated individuals. Frontiers in immunology, 14, 1166589. https://doi.org/10.3389/fimmu.2023.1166589

Bošnjak, B., Lueder, Y., Messerle, M., & Förster, R. (2023). Imaging cytomegalovirus infection and ensuing immune responses. Current opinion in immunology, 82, 102307. https://doi.org/10.1016/j.coi.2023.102307

Grychtol, R., Riemann, L., Gaedcke, S., Liu, B., DeLuca, D., Förster, R., Maison, N., Thiele, D., Jakobs, N., Bahmer, T., Meyer, M., Foth, S., Weber, S., Rietschel, E., Rabe, K. F., Kopp, M. V., von Mutius, E., Dittrich, A. M., Hansen, G., & ALLIANCE Study Group as part of the German Center for Lung Research (DZL) (2023). Validation of the Asthma Severity Scoring System (ASSESS) in the ALLIANCE Cohort. The Journal of allergy and clinical immunology, 151(6), 1525–1535.e4. https://doi.org/10.1016/j.jaci.2023.01.027

Zhang, B., Zhang, Z., Koeken, V. A. C. M., Kumar, S., Aillaud, M., Tsay, H. C., Liu, Z., Kraft, A. R. M., Soon, C. F., Odak, I., Bošnjak, B., Vlot, A., Deutsche COVID-19 OMICS Initiative (DeCOI), Swertz, M. A., Ohler, U., Geffers, R., Illig, T., Huehn, J., Saliba, A. E., Sander, L. E., … Li, Y. (2023). Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19. Cell genomics, 3(2), 100232. https://doi.org/10.1016/j.xgen.2022.100232

Yang T, Barros-Martins J, Janssen A, Wang Z, León-Lara X, Weiss S, Prinz I, Förster R, Ravens S (2023). Adult thymus-derived cMaf+RORγt+ γδ T cells lack Scart2 chromatin accessibility and do not reach periphery. doi: https://doi.org/10.1101/2023.02.20.529224

2022

Odak, I., Sikora, R., Riemann, L., Bayir, L. M., Beck, M., Drenker, M., Xiao, Y., Schneider, J., Dammann, E., Stadler, M., Eder, M., Ganser, A., Förster, R., Koenecke, C., & Schultze-Florey, C. R. (2022). Spectral flow cytometry cluster analysis of therapeutic donor lymphocyte infusions identifies T cell subsets associated with outcome in patients with AML relapse. Frontiers in immunology, 13, 999163. https://doi.org/10.3389/fimmu.2022.999163

Odak, I., Förster, R., & Bošnjak, B. (2022). Hide and seek with SARS-CoV-2: spike receptor-binding domain-specific memory B cells still recognize Omicron variant. Signal transduction and targeted therapy, 7(1), 343. https://doi.org/10.1038/s41392-022-01192-8

Schneider J, Kuhlmann L, Xiao Y, Raha S, Bernhardt G, Stadler M, Thol F, Heuser M, Eder M, Ganser A, Ravens S, Förster R, Prinz I, Koenecke C, Schultze-Florey CR. Healthy-like CD4+ Regulatory and CD4+ Conventional T-Cell Receptor Repertoires Predict Protection from GVHD Following Donor Lymphocyte Infusion. Int J Mol Sci. 2022 Sep 18;23(18):10914. doi: 10.3390/ijms231810914. PMID: 36142824; PMCID: PMC9505302.

Behrens GMN, Barros-Martins J, Cossmann A, Ramos GM, Stankov MV, Odak I, Dopfer-Jablonka A, Hetzel L, Köhler M, Patzer G, Binz C, Ritter C, Friedrichsen M, Schultze-Florey C, Ravens I, Willenzon S, Bubke A, Ristenpart J, Janssen A, Ssebyatika G, Krähling V, Bernhardt G, Hoffmann M, Pöhlmann S, Krey T, Bošnjak B, Hammerschmidt SI, Förster R. BNT162b2-boosted immune responses six months after heterologous or homologous ChAdOx1nCoV-19/BNT162b2 vaccination against COVID-19. Nat Commun. 2022 Aug 18;13(1):4872. doi: 10.1038/s41467-022-32527-2. PMID: 35982040; PMCID: PMC9387891.

Fleig S, Kapanadze T, Bernier-Latmani J, Lill JK, Wyss T, Gamrekelashvili J, Kijas D, Liu B, Hüsing AM, Bovay E, Jirmo AC, Halle S, Ricke-Hoch M, Adams RH, Engel DR, von Vietinghoff S, Förster R, Hilfiker-Kleiner D, Haller H, Petrova TV, Limbourg FP. Loss of vascular endothelial notch signaling promotes spontaneous formation of tertiary lymphoid structures. Nat Commun. 2022 Apr 19;13(1):2022. doi: 10.1038/s41467-022-29701-x. PMID: 35440634; PMCID: PMC9018798.

Odak I, Schultze-Florey CR, Hammerschmidt SI, Ritter C, Willenzon S, Friedrichsen M, Ravens I, Sikora R, Bayir LM, Gutierrez Jauregui R, Bernhardt G, Stankov MV, Cossmann A, Hansen G, Krey T, Cornberg M, Koenecke C, Behrens GMN, Bošnjak B, Förster R. Longitudinal Tracking of Immune Responses in COVID-19 Convalescents Reveals Absence of Neutralization Activity Against Omicron and Staggered Impairment to Other SARS-CoV-2 Variants of Concern. Front Immunol. 2022 Mar 14;13:863039. doi: 10.3389/fimmu.2022.863039. PMID: 35359969; PMCID: PMC8964088.

Froese N, Cordero J, Abouissa A, Trogisch FA, Grein S, Szaroszyk M, Wang Y, Gigina A, Korf-Klingebiel M, Bosnjak B, Davenport CF, Wiehlmann L, Geffers R, Riechert E, Jürgensen L, Boileau E, Lin Y, Dieterich C, Förster R, Bauersachs J, Ola R, Dobreva G, Völkers M, Heineke J. Analysis of myocardial cellular gene expression during pressure overload reveals matrix based functional intercellular communication. iScience. 2022 Feb 23;25(3):103965. doi: 10.1016/j.isci.2022.103965. PMID: 35281736; PMCID: PMC8908217.

Rezalotfi A, Fritz L, Förster R, Bošnjak B. Challenges of CRISPR-Based Gene Editing in Primary T Cells. Int J Mol Sci. 2022 Feb 1;23(3):1689. doi: 10.3390/ijms23031689. PMID: 35163611; PMCID: PMC8835901.

Barros-Martins J, Förster R, Bošnjak B. NK cell dysfunction in severe COVID-19: TGF-β-induced downregulation of integrin beta-2 restricts NK cell cytotoxicity. Signal Transduct Target Ther. 2022 Jan 31;7(1):32. doi: 10.1038/s41392-022-00892-5. PMID: 35102142; PMCID: PMC8801552.

Menon MB, Yakovleva T, Ronkina N, Suwandi A, Odak I, Dhamija S, Sandrock I, Hansmann F, Baumgärtner W, Förster R, Kotlyarov A, Gaestel M. Lyz2-Cre-Mediated Genetic Deletion of Septin7 Reveals a Role of Septins in Macrophage Cytokinesis and Kras-Driven Tumorigenesis. Front Cell Dev Biol. 2022 Jan 6;9:795798. doi: 10.3389/fcell.2021.795798. PMID: 35071236; PMCID: PMC8772882.

Hammerschmidt SI, Thurm C, Bošnjak B, Bernhardt G, Reinhold A, Willenzon S, Ritter C, Reinhold D, Schraven B, Förster R. Robust induction of neutralizing antibodies against the SARS-CoV-2 Delta variant after homologous Spikevax or heterologous Vaxzevria-Spikevax vaccination. Eur J Immunol. 2022 Feb;52(2):356-359. doi: 10.1002/eji.202149645. Epub 2022 Jan 7. PMID: 34870322.

2021

Bošnjak B, Do KTH, Förster R, Hammerschmidt SI. Imaging dendritic cell functions. Immunol Rev. 2021 Dec 3. doi: 10.1111/imr.13050. Epub ahead of print. PMID: 34859450.

Bošnjak B, Odak I, Barros-Martins J, Sandrock I, Hammerschmidt SI, Permanyer M, Patzer GE, Greorgiev H, Gutierrez Jauregui R, Tscherne A, Schwarz JH, Kalodimou G, Ssebyatika G, Ciurkiewicz M, Willenzon S, Bubke A, Ristenpart J, Ritter C, Tuchel T, Meyer Zu Natrup C, Shin DL, Clever S, Limpinsel L, Baumgärtner W, Krey T, Volz A, Sutter G, Förster R. Intranasal Delivery of MVA Vector Vaccine Induces Effective Pulmonary Immunity Against SARS-CoV-2 in Rodents. Front Immunol. 2021 Nov 11;12:772240. doi: 10.3389/fimmu.2021.772240. PMID: 34858430; PMCID: PMC8632543.

Zhu S, Stanslowsky N, Fernández-Trillo J, Mamo TM, Yu P, Kalmbach N, Ritter B, Eggenschwiler R, Ouwendijk WJD, Mzinza D, Tan L, Leffler A, Spohn M, Brown RJP, Kropp KA, Kaever V, Ha TC, Narayanan P, Grundhoff A, Förster R, Schambach A, Verjans GMGM, Schmidt M, Kispert A, Cantz T, Gomis A, Wegner F, Viejo-Borbolla A. Generation of hiPSC-derived low threshold mechanoreceptors containing axonal termini resembling bulbous sensory nerve endings and expressing Piezo1 and Piezo2. Stem Cell Res. 2021 Oct;56:102535. doi: 10.1016/j.scr.2021.102535. Epub 2021 Sep 11. PMID: 34607262.

Hammerschmidt SI, Bosnjak B, Bernhardt G, Friedrichsen M, Ravens I, Dopfer-Jablonka A, Hoffmann M, Pöhlmann S, Behrens GMN, Förster R. Neutralization of the SARS-CoV-2 Delta variant after heterologous and homologous BNT162b2 or ChAdOx1 nCoV-19 vaccination. Cell Mol Immunol. 2021 Oct;18(10):2455-2456. doi: 10.1038/s41423-021-00755-z. Epub 2021 Aug 23. PMID: 34426672; PMCID: PMC8381713.

Bošnjak B, Odak I, Ritter C, Stahl K, Graalmann T, Steinbrück L, Blasczyk R, Falk CS, Schulz TF, Wedemeyer HH, Cornberg M, Ganser A, Förster R, Koenecke C. Case Report: Convalescent Plasma Therapy Induced Anti-SARS-CoV-2 T Cell Expansion, NK Cell Maturation and Virus Clearance in a B Cell Deficient Patient After CD19 CAR T Cell Therapy. Front Immunol. 2021 Aug 12;12:721738. doi: 10.3389/fimmu.2021.721738. PMID: 34456929; PMCID: PMC8387963.

Schultze-Florey CR, Kuhlmann L, Raha S, Barros-Martins J, Odak I, Tan L, Xiao Y, Ravens S, Hambach L, Venturini L, Stadler M, Eder M, Thol F, Heuser M, Forster R, Ganser A, Prinz I, Koenecke C. Clonal expansion of CD8+ T cells reflects graft-versus-leukemia activity and precedes durable remission following DLI. Blood Adv. 2021 Sep 17:bloodadvances.2020004073. doi: 10.1182/bloodadvances.2020004073. Epub ahead of print. PMID: 34535011.

Tscherne A, Schwarz JH, Rohde C, Kupke A, Kalodimou G, Limpinsel L, Okba NMA, Bošnjak B, Sandrock I, Odak I, Halwe S, Sauerhering L, Brosinski K, Liangliang N, Duell E, Jany S, Freudenstein A, Schmidt J, Werner A, Gellhorn Serra M, Klüver M, Guggemos W, Seilmaier M, Wendtner CM, Förster R, Haagmans BL, Becker S, Sutter G, Volz A. Immunogenicity and efficacy of the COVID-19 candidate vector vaccine MVA-SARS-2-S in preclinical vaccination. Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2026207118. doi: 10.1073/pnas.2026207118. PMID: 34162739; PMCID: PMC8285915.

Barros-Martins J, Hammerschmidt SI, Cossmann A, Odak I, Stankov MV, Morillas Ramos G, Dopfer-Jablonka A, Heidemann A, Ritter C, Friedrichsen M, Schultze-Florey C, Ravens I, Willenzon S, Bubke A, Ristenpart J, Janssen A, Ssebyatika G, Bernhardt G, Münch J, Hoffmann M, Pöhlmann S, Krey T, Bošnjak B, Förster R, Behrens GMN. Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination. Nat Med. 2021 Jul 14. doi: 10.1038/s41591-021-01449-9. Epub ahead of print. PMID: 34262158.

Werth K, Hub E, Gutjahr JC, Bosjnak B, Zheng X, Bubke A, Russo S, Rot A, Förster R. Expression of ACKR4 demarcates the "peri-marginal sinus," a specialized vascular compartment of the splenic red pulp. Cell Rep. 2021 Jul 13;36(2):109346. doi: 10.1016/j.celrep.2021.109346. PMID: 34260918.

Yu K, Hammerschmidt SI, Permanyer M, Galla M, Rothe M, Zheng X, Werth K, Martens R, Lueder Y, Janssen A, Friedrichsen M, Bernhardt G, Förster R. Targeted delivery of regulatory macrophages to lymph nodes interferes with T cell priming by preventing the formation of stable immune synapses. Cell Rep. 2021 Jun 22;35(12):109273. doi: 10.1016/j.celrep.2021.109273. PMID: 34161766.

Ghita L, Spanier J, Chhatbar C, Mulenge F, Pavlou A, Larsen PK, Waltl I, Lueder Y, Kohls M, Jung K, Best SM, Förster R, Stangel M, Schreiner D, Kalinke U. MyD88 signaling by neurons induces chemokines that recruit protective leukocytes to the virus-infected CNS. Sci Immunol. 2021 Jun 25;6(60):eabc9165. doi: 10.1126/sciimmunol.abc9165. PMID: 34172587.

de Castro Pinho J, Förster R. Lymph-Derived Neutrophils Primarily Locate to the Subcapsular and Medullary Sinuses in Resting and Inflamed Lymph Nodes. Cells. 2021 Jun 12;10(6):1486. doi: 10.3390/cells10061486. PMID: 34204825; PMCID: PMC8231499.

Nikolova G, Weiss S, Bosnjak B, Förster R. Differential retention of lymph-borne CD8 memory T cell subsets in the subcapsular sinus of resting and inflamed lymph nodes. Cell Mol Immunol. 2021 May;18(5):1317-1319. doi: 10.1038/s41423-020-0451-6. Epub 2020 May 12. PMID: 32398805; PMCID: PMC8093287.

Durán V, Grabski E, Hozsa C, Becker J, Yasar H, Monteiro JT, Costa B, Koller N, Lueder Y, Wiegmann B, Brandes G, Kaever V, Lehr CM, Lepenies B, Tampé R, Förster R, Bošnjak B, Furch M, Graalmann T, Kalinke U. Fucosylated lipid nanocarriers loaded with antibiotics efficiently inhibit mycobacterial propagation in human myeloid cells. J Control Release. 2021 Jun 10;334:201-212. doi: 10.1016/j.jconrel.2021.04.012. Epub 2021 Apr 16. PMID: 33865899.

Schultze-Florey CR, Chukhno E, Goudeva L, Blasczyk R, Ganser A, Prinz I, Förster R, Koenecke C, Odak I. Distribution of major lymphocyte subsets and memory T-cell subpopulations in healthy adults employing GLP-conforming multicolor flow cytometry. Leukemia. 2021 Jul 21. doi: 10.1038/s41375-021-01348-5. Epub ahead of print. PMID: 34290358.

Tan L, Fichtner AS, Bruni E, Odak I, Sandrock I, Bubke A, Borchers A, Schultze-Florey C, Koenecke C, Förster R, Jarek M, von Kaisenberg C, Schulz A, Chu X, Zhang B, Li Y, Panzer U, Krebs CF, Ravens S, Prinz I. A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood. Sci Immunol. 2021 Apr 23;6(58):eabf0125. doi: 10.1126/sciimmunol.abf0125. PMID: 33893173.

Permanyer M, Bošnjak B, Glage S, Friedrichsen M, Floess S, Huehn J, Patzer GE, Odak I, Eckert N, Zargari R, Ospina-Quintero L, Georgiev H, Förster R. Efficient IL-2R signaling differentially affects the stability, function, and composition of the regulatory T-cell pool. Cell Mol Immunol. 2021 Feb;18(2):398-414. doi: 10.1038/s41423-020-00599-z. Epub 2021 Jan 6. PMID: 33408345; PMCID: PMC8027001.

2020

Willers M, Ulas T, Völlger L, Vogl T, Heinemann AS, Pirr S, Pagel J, Fehlhaber B, Halle O, Schöning J, Schreek S, Löber U, Essex M, Hombach P, Graspeuntner S, Basic M, Bleich A, Cloppenborg-Schmidt K, Künzel S, Jonigk D, Rupp J, Hansen G, Förster R, Baines JF, Härtel C, Schultze JL, Forslund SK, Roth J, Viemann D. S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants. Gastroenterology. 2020 Dec;159(6):2130-2145.e5. doi: 10.1053/j.gastro.2020.08.019. Epub 2020 Aug 15. PMID: 32805279.

Behrens GMN, Cossmann A, Stankov MV, Schulte B, Streeck H, Förster R, Bosnjak B, Willenzon S, Boeck AL, Thu Tran A, Thiele T, Graalmann T, Kayser MZ, Zychlinsky Scharff A, Dopfer C, Horke A, Pink I, Witte T, Wetzke M, Ernst D, Jablonka A, Happle C. Strategic Anti-SARS-CoV-2 Serology Testing in a Low Prevalence Setting: The COVID-19 Contact (CoCo) Study in Healthcare Professionals. Infect Dis Ther. 2020 Dec;9(4):837-849. doi: 10.1007/s40121-020-00334-1. Epub 2020 Sep 4. PMID: 32886335; PMCID: PMC7472691.

Förster R, Fleige H, Sutter G. Combating COVID-19: MVA Vector Vaccines Applied to the Respiratory Tract as Promising Approach Toward Protective Immunity in the Lung. Front Immunol. 2020 Aug 7;11:1959. doi: 10.3389/fimmu.2020.01959. PMID: 32849655; PMCID: PMC7426738.

Bošnjak B, Stein SC, Willenzon S, Cordes AK, Puppe W, Bernhardt G, Ravens I, Ritter C, Schultze-Florey CR, Gödecke N, Martens J, Kleine-Weber H, Hoffmann M, Cossmann A, Yilmaz M, Pink I, Hoeper MM, Behrens GMN, Pöhlmann S, Blasczyk R, Schulz TF, Förster R. Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods. Cell Mol Immunol. 2020 Nov 2:1–9. doi: 10.1038/s41423-020-00573-9. Epub ahead of print. PMID: 33139905; PMCID: PMC7604543.

Odak, I., Barros-Martins, J., Bošnjak, B., Stahl, K., David, S., Wiesner, O., Busch, M., Hoeper, M. M., Pink, I., Welte, T., Cornberg, M., Stoll, M., Goudeva, L., Blasczyk, R., Ganser, A., Prinz, I., Förster, R., Koenecke, C., & Schultze-Florey, C. R. Reappearance of effector T cells is associated with recovery from COVID-19 [published online ahead of print, 2020 Jul 7]. EBioMedicine. 2020;57:102885. doi:10.1016/j.ebiom.2020.102885

Odak I, Depkat-Jakob A, Beck M, Jarek M, Yu Y, Seidler U, David S, Ganser A, Förster R*, Prinz I*, Koenecke C*. Donor-derived IL-17A and IL-17F deficiency triggers Th1 allo-responses and increases gut leakage during acute GVHD. PLoS One. 2020 Apr 6;15(4):e0231222. doi: 10.1371/journal.pone.0231222. eCollection 2020. PubMed PMID: 32251446.
* These authors contributed equally to this work

Martens R, Permanyer M, Werth K, Yu K, Braun A, Halle O, Halle S, Patzer GE, Bošnjak B, Kiefer F, Janssen A, Friedrichsen M, Poetzsch J, Kohli K, Lueder Y, Gutierrez Jauregui R, Eckert N, Worbs T, Galla M, Förster R. Efficient homing of T cells via afferent lymphatics requires mechanical arrest and integrin-supported chemokine guidance. Nat Commun. 2020 Feb 28;11(1):1114. doi: 10.1038/s41467-020-14921-w. PMID: 32111837; PMCID: PMC7048855.

2019

Eckert N, Werth K, Willenzon S, Tan L, Förster R. B cell hyperactivation in an Ackr4-deficient mouse strain is not caused by lack of ACKR4 expression. J Leukoc Biol. 2019 Dec 16. doi: 10.1002/JLB.2MA1119-300R. [Epub ahead of print] PubMed PMID: 31841228.

Bickes MS, Pirr S, Heinemann AS, Fehlhaber B, Halle S, Völlger L, Willers M, Richter M, Böhne C, Albrecht M, Langer M, Pfeifer S, Jonigk D, Vieten G, Ure B, von Kaisenberg C, Förster R, von Köckritz-Blickwede M, Hansen G, Viemann D. Constitutive TNF-α signaling in neonates is essential for the development of tissue-resident leukocyte profiles at barrier sites. FASEB J. 2019 Oct;33(10):10633-10647. doi: 10.1096/fj.201900796R. Epub 2019 Jun 29. PubMed PMID: 31262195.

O'Connor T, Zhou X, Kosla J, Adili A, Garcia Beccaria M, Kotsiliti E, Pfister D, Johlke AL, Sinha A, Sankowski R, Schick M, Lewis R, Dokalis N, Seubert B, Höchst B, Inverso D, Heide D, Zhang W, Weihrich P, Manske K, Wohlleber D, Anton M, Hoellein A, Seleznik G, Bremer J, Bleul S, Augustin HG, Scherer F, Koedel U, Weber A, Protzer U, Förster R, Wirth T, Aguzzi A, Meissner F, Prinz M, Baumann B, Höpken UE, Knolle PA, von Baumgarten L, Keller U, Heikenwalder M. Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention. Cancer Cell. 2019 Sep 16;36(3):250-267.e9. doi: 10.1016/j.ccell.2019.08.001. PMID: 31526758.

Gutierrez Jauregui R, Fleige H, Bubke A, Rohde M, Weiss S, Förster R. IL-1β Promotes Staphylococcus aureus Biofilms on Implants in vivo. Front Immunol. 2019 May 17;10:1082. doi: 10.3389/fimmu.2019.01082. eCollection 2019. PubMed PMID: 31156635; PubMed Central PMCID: PMC6534041.

Odak I*, Raha S*, Schultze-Florey C, Tavil S, Ravens S, Ganser A, Förster R, Prinz I**, Koenecke C**. Focusing of the regulatory T cell repertoire after allogeneic stem cell transplantation indicates protection from graft-versus-host disease. Haematologica. 2019 Apr 24. pii: haematol.2019.218206. doi: 10.3324/haematol.2019.218206. [Epub ahead of print] PubMed PMID: 31018979.
*equal contribution, ** shared senior authorship

Eckert N, Permanyer M, Yu K, Werth K, Förster R. Chemokines and other mediators in the development and functional organization of lymph nodes. Immunol Rev. 2019 May;289(1):62-83. doi: 10.1111/imr.12746. Review. PubMed PMID: 30977201.

Wilharm A, Tabib Y, Nassar M, Reinhardt A, Mizraji G, Sandrock I, Heyman O, Barros-Martins J, Aizenbud Y, Khalaileh A, Eli-Berchoer L, Elinav E, Wilensky A, Förster R, Bercovier H, Prinz I, Hovav AH. Mutual interplay between IL-17-producing γδT cells and microbiota orchestrates oral mucosal homeostasis. Proc Natl Acad Sci U S A. 2019 Jan 28. pii: 201818812. doi: 10.1073/pnas.1818812116. [Epub ahead of print] PubMed PMID: 30692259

2018:

Sandrock I, Reinhardt A, Ravens S, Binz C, Wilharm A, Martins J, Oberdörfer L, Tan L, Lienenklaus S, Zhang B, Naumann R, Zhuang Y, Krueger A, Förster R, Prinz I. Genetic models reveal origin, persistence and non-redundant functions of IL-17-producing γδ T cells. J Exp Med. 2018 Nov 19. pii: jem.20181439.

Pägelow D, Chhatbar C, Beineke A, Liu X, Nerlich A, van Vorst K, Rohde M, Kalinke U, Förster R, Halle S, Valentin-Weigand P, Hornef MW, Fulde M. The olfactory epithelium as a port of entry in neonatal neurolisteriosis. Nat Commun. 2018 Oct 15;9(1):4269. doi: 10.1038/s41467-018-06668-2. PubMed PMID: 30323282; PubMed Central PMCID: PMC6189187

Mzinza DT, Fleige H, Laarmann K, Willenzon S, Ristenpart J, Spanier J, Sutter G, Kalinke U, Valentin-Weigand P, Förster R. Application of light sheet microscopy for qualitative and quantitative analysis of bronchus-associated lymphoid tissue in mice. Cell Mol Immunol. 2018 Oct;15(10):875-887. doi: 10.1038/cmi.2017.150. Epub 2018 Feb 12. PubMed PMID: 29429996; PubMed Central PMCID: PMC6207560

Hammerschmidt SI, Werth K, Rothe M, Galla M, Permanyer M, Patzer GE, Bubke A, Frenk DN, Selich A, Lange L, Schambach A, Bošnjak B, Förster R. CRISPR/Cas9 Immunoengineering of Hoxb8-Immortalized Progenitor Cells for Revealing CCR7-Mediated Dendritic Cell Signaling and Migration Mechanisms in vivo. Front Immunol. 2018 Aug 28;9:1949. doi: 10.3389/fimmu.2018.01949. eCollection 2018. PubMed PMID: 30210501; PubMed Central PMCID: PMC6120996

Lueder Y, Heller K, Ritter C, Keyser KA, Wagner K, Liu X, Messerle M, Stahl FR, Halle S, Förster R. Control of primary mouse cytomegalovirus infection in lung nodular inflammatory foci by cooperation of interferon-gamma expressing CD4 and CD8 T cells. PLoS Pathog. 2018 Aug 28;14(8):e1007252. doi: 10.1371/journal.ppat.1007252. eCollection 2018 Aug. PubMed PMID: 30153311; PubMed Central PMCID: PMC6112668

Permanyer M, Bošnjak B, Förster R. Dendritic cells, T cells and lymphatics: dialogues in migration and beyond. Curr Opin Immunol. 2018 Aug;53:173-179. doi: 10.1016/j.coi.2018.05.004. Epub 2018 May 29. Review. PubMed PMID: 29857205

Moschovakis GL, Bubke A, Friedrichsen M, Ristenpart J, Back JW, Falk CS, Kremmer E, Förster R. The chemokine receptor CCR7 is a promising target for rheumatoid arthritis therapy. Cell Mol Immunol. 2018 Jul 4. doi: 10.1038/s41423-018-0056-5. [Epub ahead of print] PubMed PMID: 29973648

Fleige H, Bosnjak B, Permanyer M, Ristenpart J, Bubke A, Willenzon S, Sutter G, Luther SA, Förster R. Manifold Roles of CCR7 and Its Ligands in the Induction and Maintenance of Bronchus-Associated Lymphoid Tissue. Cell Rep. 2018 Apr 17;23(3):783-795. doi: 10.1016/j.celrep.2018.03.072. PubMed PMID: 29669284.

Georgiev, H., Ravens, I., Papadogianni, G., Halle, S., Malissen, B., Loots, G. G., Förster, R., and Bernhardt, G. (2018). Shared and unique features distinguishing follicular T helper and regulatory cells of peripheral lymph node and Peyer's Patches. Front Immunol

Georgiev H, Ravens I, Papadogianni G, Malissen B, Förster R, Bernhardt G. Blocking the ART2.2/P2 × 7-system is essential to avoid a detrimental bias in functional CD4 T cell studies. Eur J Immunol. 2018 Mar 5. doi: 10.1002/eji.201747420. [Epub ahead of print] PubMed PMID: 29508376

Hetzel M, Mucci A, Blank P, Nguyen AHH, Schiller J, Halle O, Kühnel MP, Billig S, Meineke R, Brand D, Herder V, Baumgärtner W, Bange FC, Goethe R, Jonigk D, Förster R, Gentner B, Casanova JL, Bustamante J, Schambach A, Kalinke U, Lachmann N. Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections. Blood. 2018 Feb 1;131(5):533-545. doi: 10.1182/blood-2017-10-812859. Epub 2017 Dec 12. PubMed PMID: 29233822.

2017:

Pezoldt J, Pisano F, Heine W, Pasztoi M, Rosenheinrich M, Nuss AM, Pils MC, Prinz I, Förster R, Huehn J, Dersch P. Impact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection. J Infect Dis. 2017 Sep 15;216(6):752-760. doi: 10.1093/infdis/jix037. PubMed PMID: 28329174.

Permanyer M, Bošnjak B, Förster R. Dual role for atypical chemokine receptor 1 in myeloid cell hematopoiesis and distribution. Cell Mol Immunol. 2017 Sep 4. doi: 10.1038/cmi.2017.79. [Epub ahead of print] PubMed PMID: 29532789.

Moschovakis GL, Bubke A, Friedrichsen M, Falk CS, Feederle R, Förster R. T cell specific Cxcr5 deficiency prevents rheumatoid arthritis. Sci Rep. 2017 Aug 21;7(1):8933. doi: 10.1038/s41598-017-08935-6. PubMed PMID: 28827539; PubMed Central PMCID: PMC5567121.

Halle S, Halle O, Förster R. Mechanisms and Dynamics of T Cell-Mediated Cytotoxicity In Vivo. Trends Immunol. 2017 Jun;38(6):432-443. doi: 10.1016/j.it.2017.04.002. Epub 2017 May 9. Review. PubMed PMID: 28499492.

Moschovakis GL, Förster R. Repulsive behavior in germinal centers. Science. 2017 May 19; 356(6339):703-704. doi: 10.1126/science.aan5222. PubMed PMID: 28522496.

Ravens S, Schultze-Florey C, Raha S, Sandrock I, Drenker M, Oberdörfer L, Reinhardt A, Ravens I, Beck M, Geffers R, von Kaisenberg C, Heuser M, Thol F, Ganser A, Förster R, Koenecke C, Prinz I. Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection. Nat Immunol. 2017 Feb 20. doi: 10.1038/ni.3686. [Epub ahead of print] PubMed PMID: 28218745

Fleige H, Förster R. Induction and Analysis of Bronchus-Associated Lymphoid Tissue. Methods Mol Biol. 2017;1559:185-198. doi: 10.1007/978-1-4939-6786-5_13. PubMed PMID: 28063045.

Worbs T, Hammerschmidt SI, Förster R. Dendritic cell migration in health and disease. Nat Rev Immunol. 2017 Jan;17(1):30-48. doi: 10.1038/nri.2016.116. PubMed PMID: 27890914.


2016:

Kohli K, Janssen A, Förster R. Plasmacytoid dendritic cells induce tolerance predominantly by cargoing antigen to lymph nodes. Eur J Immunol. 2016 Nov;46(11):2659-2668. doi: 10.1002/eji.201646359. PubMed PMID: 27592607; PubMed Central PMCID: PMC5129535.

Georgiev H, Ravens I, Benarafa C, Förster R, Bernhardt G. Distinct gene expression patterns correlate with developmental and functional traits of iNKT subsets. Nat Commun. 2016 Oct 10;7:13116. doi: 10.1038/ncomms13116. PubMed PMID:
27721447.

Reinhardt A, Yevsa T, Worbs T, Lienenklaus S, Sandrock I, Oberdörfer L, Korn T, Weiss S, Förster R, Prinz I. Interleukin-23-Dependent γ/δ T Cells Produce Interleukin-17 and Accumulate in the Enthesis, Aortic Valve, and Ciliary Body in Mice. Arthritis Rheumatol. 2016 Oct;68(10):2476-86. doi: 10.1002/art.39732. PubMed PMID: 27111864.

Zheng X, Halle S, Yu K, Mishra P, Scherr M, Pietzsch S, Willenzon S, Janssen A, Boelter J, Hilfiker-Kleiner D, Eder M, Förster R. Cardiomyocytes display low mitochondrial priming and are highly resistant toward cytotoxic T-cell killing. Eur J Immunol. 2016 Jun;46(6):1415-26. doi: 10.1002/eji.201546080. Epub 2016 Mar 31. Erratum in: Eur J Immunol. 2016 Aug;46(8):2054. PubMed PMID: 26970349; PubMed Central PMCID: PMC5071700.

Schulz O, Hammerschmidt SI, Moschovakis GL, Förster R. Chemokines and Chemokine Receptors in Lymphoid Tissue Dynamics. Annu Rev Immunol. 2016 May 20;34:203-42. doi: 10.1146/annurev-immunol-041015-055649. Epub 2016 Feb 22. Review. PubMed PMID: 26907216.

Gupta SK, Itagaki R, Zheng X, Batkai S, Thum S, Ahmad F, Van Aelst LN, Sharma A, Piccoli MT, Weinberger F, Fiedler J, Heuser M, Heymans S, Falk CS, Förster R, Schrepfer S, Thum T. miR-21 promotes fibrosis in an acute cardiac allograft transplantation model. Cardiovasc Res. 2016 May 15;110(2):215-26. doi: 10.1093/cvr/cvw030. Epub 2016 Feb 9. PubMed PMID: 26865549.

Ivanov S, Scallan JP, Kim KW, Werth K, Johnson MW, Saunders BT, Wang PL, Kuan EL, Straub AC, Ouhachi M, Weinstein EG, Williams JW, Briseño C, Colonna M, Isakson BE, Gautier EL, Förster R, Davis MJ, Zinselmeyer BH, Randolph GJ. CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability. J Clin Invest. 2016 Apr 1;126(4):1581-91. doi: 10.1172/JCI84518. Epub 2016 Mar 21. PubMed PMID: 26999610; PubMed Central PMCID: PMC4811132.

Lee CW, Wohlan K, Dallmann I, Förster R, Ganser A, Krueger A, Scherr M, Eder M, Koenecke C. miR-181a Expression in Donor T Cells Modulates Graft-versus-Host Disease after Allogeneic Bone Marrow Transplantation. J Immunol. 2016 May 1;196(9):3927-34. doi: 10.4049/jimmunol.1502152. Epub 2016 Mar 23. PubMed PMID: 27009493.

Georgiev H, Ravens I, Shibuya A, Förster R, Bernhardt G. CD155/CD226-interaction impacts on the generation of innate CD8(+) thymocytes by regulating iNKT-cell differentiation. Eur J Immunol. 2016 Apr;46(4):993-1003. doi: 10.1002/eji.201546073. Epub 2016 Jan 20. PubMed PMID: 26689152.

Halle S, Keyser KA, Stahl FR, Busche A, Marquardt A, Zheng X, Galla M, Heissmeyer V, Heller K, Boelter J, Wagner K, Bischoff Y, Martens R, Braun A, Werth K, Uvarovskii A, Kempf H, Meyer-Hermann M, Arens R, Kremer M, Sutter G, Messerle M, Förster R. In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity. Immunity. 2016 Feb 16;44(2):233-45. doi: 10.1016/j.immuni.2016.01.010. Epub 2016 Feb 9. PubMed PMID: 26872694; PubMed Central PMCID: PMC4846978.

Förster R, Worbs T, Werth K. A 4-midable Connection: CCR7 Tetramers Link GPCR to Src Kinase Signaling. Immunity. 2016 Jan 19;44(1):9-11. doi: 10.1016/j.immuni.2015.12.009. PubMed PMID: 26789916.

Kiermaier E, Moussion C, Veldkamp CT, Gerardy-Schahn R, de Vries I, Williams LG, Chaffee GR, Phillips AJ, Freiberger F, Imre R, Taleski D, Payne RJ, Braun A, Förster R, Mechtler K, Mühlenhoff M, Volkman BF, Sixt M. Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. Science. 2016 Jan 8;351(6269):186-90. doi: 10.1126/science.aad0512. Epub 2015 Dec 10. PubMed PMID: 26657283.

Werth K, Förster R. Active Shaping of Chemokine Gradients by Atypical Chemokine Receptors: A 4D Live-Cell Imaging Migration Assay. Methods Enzymol. 2016;570:293-308. doi: 10.1016/bs.mie.2015.09.008. Epub 2015 Dec 14. PubMed PMID: 26921952.

Förster R, Schubel A, Breitfeld D, Kremmer E, Renner-Müller I, Wolf E, Lipp M. Pillars Article: CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs. Cell. 1999. 99: 23-33. J Immunol. 2016 Jan 1;196(1):5-15. PubMed PMID: 26685313.

2015

Ziętara N, Łyszkiewicz M, Puchałka J, Witzlau K, Reinhardt A, Förster R, Pabst O, Prinz I, Krueger A. Multicongenic fate mapping quantification of dynamics of thymus colonization. J Exp Med. 2015 Sep 21;212(10):1589-601. doi: 10.1084/jem.20142143. Epub 2015 Sep 7. PubMed PMID: 26347471; PubMed Central PMCID: PMC4577840.

Torow N, Yu K, Hassani K, Freitag J, Schulz O, Basic M, Brennecke A, Sparwasser T, Wagner N, Bleich A, Lochner M, Weiss S, Förster R, Pabst O, Hornef MW. Active suppression of intestinal CD4(+)TCRαβ(+) T-lymphocyte maturation during the postnatal period. Nat Commun. 2015 Jul 21;6:7725. doi: 10.1038/ncomms8725. PubMed PMID: 26195040; PubMed Central PMCID: PMC4518322.

Schreder A, Moschovakis GL, Halle S, Schlue J, Lee CW, Schippers A, David S, Bernhardt G, Ganser A, Pabst O, Förster R, Koenecke C. Differential Effects of Gut-Homing Molecules CC Chemokine Receptor 9 and Integrin-β7 during Acute Graft-versus-Host Disease of the Liver. Biol Blood Marrow Transplant. 2015 Dec;21(12):2069-78. doi: 10.1016/j.bbmt.2015.08.038. Epub 2015 Sep 5. PubMed PMID: 26348893.

2014

Ulvmar MH, Werth K, Braun A, Kelay P, Hub E, Eller K, Chan L, Lucas B, Novitzky-Basso I, Nakamura K, Rülicke T, Nibbs RJ, Worbs T, Förster R, Rot A. The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes. Nat Immunol. 2014 Jul;15(7):623-30. doi: 10.1038/ni.2889. Epub 2014 May 11. PubMed PMID: 24813163.

Stahl FR, Keyser KA, Heller K, Bischoff Y, Halle S, Wagner K, Messerle M, Förster R. Mck2-dependent infection of alveolar macrophages promotes replication of MCMV in nodular inflammatory foci of the neonatal lung. Mucosal Immunol. 2015 Jan;8(1):57-67. doi: 10.1038/mi.2014.42. Epub 2014 Jun 4. PubMed PMID: 24894498.

Reinhardt A, Ravens S, Fleige H, Haas JD, Oberdörfer L, Łyszkiewicz M, Förster R, Prinz I. CCR7-mediated migration in the thymus controls γδ T-cell development. Eur J Immunol. 2014 May;44(5):1320-9. doi: 10.1002/eji.201344330. Epub 2014 Mar 7. PubMed PMID: 24500801.

Menon MB, Sawada A, Chaturvedi A, Mishra P, Schuster-Gossler K, Galla M, Schambach A, Gossler A, Förster R, Heuser M, Kotlyarov A, Kinoshita M, Gaestel M. Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis. PLoS Genet. 2014 Aug 14;10(8):e1004558. doi: 10.1371/journal.pgen.1004558. eCollection 2014 Aug. PubMed PMID: 25122120; PubMed Central PMCID: PMC4133155.

Kleine M, Worbs T, Schrem H, Vondran FW, Kaltenborn A, Klempnauer J, Förster R, Josenhans C, Suerbaum S, Bektas H. Helicobacter hepaticus induces an inflammatory response in primary human hepatocytes. PLoS One. 2014 Jun 16;9(6):e99713. doi: 10.1371/journal.pone.0099713. eCollection 2014. PubMed PMID: 24932686; PubMed Central PMCID: PMC4059665.

Georgiev H, Danisch S, Chambers BJ, Shibuya A, Förster R, Bernhardt G. To the editor: TIGIT versus CD226: hegemony or coexistence? Eur J Immunol. 2014 Jan;44(1):307-8. doi: 10.1002/eji.201343925. Epub 2013 Nov 25. PubMed MID:
24166675.

Fleige H, Ravens S, Moschovakis GL, Bölter J, Willenzon S, Sutter G, Häussler S, Kalinke U, Prinz I, Förster R. IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs. J Exp Med. 2014 Apr 7;211(4):643-51. doi: 10.1084/jem.20131737. Epub 2014 Mar 24. PubMed PMID: 24663215; PubMed Central PMCID: PMC3978277.

2013:

Stahl FR, Heller K, Halle S, Keyser KA, Busche A, Marquardt A, Wagner K, Boelter J, Bischoff Y, Kremmer E, Arens R, Messerle M, Förster R. Nodular inflammatory foci are sites of T cell priming and control of murine cytomegalovirus infection in the neonatal lung. PLoS Pathog. 2013; 9(12):e1003828. doi: 10.1371/journal.ppat.1003828. Epub 2013 Dec 12. PubMed PMID: 24348257; PubMed Central PMCID: PMC3861546.

Förster R, Sozzani S. Emerging aspects of leukocyte migration. Eur J Immunol. 2013 Jun;43(6):1404-6. doi: 10.1002/eji.201343670. PubMed PMID: 23787787.

Förster R, Moschovakis GL. Orchestrating the organizers: lymphotoxin-β receptor conducts fibroblastic reticular cell maturation. Immunity. 2013 May 23;38(5):851-3

Föhse L, Reinhardt A, Oberdörfer L, Schmitz S, Förster R, Malissen B, Prinz I. Differential postselection proliferation dynamics of αβ T cells, Foxp3+ regulatory T cells, and invariant NKT cells monitored by genetic pulse labeling. J Immunol. 2013 Sep 1;191(5):2384-92. doi: 10.4049/jimmunol.1301359. Epub 2013 Jul 26. PubMed PMID: 23894200.

Danisch S, Qiu Q, Seth S, Ravens I, Dorsch M, Shibuya A, Shibuya K, Förster R, Bernhardt G. CD226 interaction with CD155 impacts on retention and negative selection of CD8 positive thymocytes as well as T cell differentiation to follicular helper cells in Peyer's Patches. Immunobiology. 2013 Feb;218(2):152-8. doi: 10.1016/j.imbio.2012.02.010. Epub 2012 Feb 17. PubMed PMID: 22429743.

2012:

Zhang X, Yu S, Hoffmann K, Yu K, Förster R. Neonatal lymph node stromal cells drive myelodendritic lineage cells into a distinct population of CX3CR1+CD11b+F4/80+ regulatory macrophages in mice. Blood. 2012 Apr 26;119(17):3975-86. doi: 10.1182/blood-2011-06-359315. Epub 2012 Mar 7. PubMed PMID: 22403256.

Peters T, Bloch W, Pabst O, Wickenhauser C, Uthoff-Hachenberg C, Schmidt SV, Varga G, Grabbe S, Kess D, Oreshkova T, Sindrilaru A, Addicks K, Förster R, Müller W, Scharffetter-Kochanek K. Adaptive immune response to model antigens is impaired in murine leukocyte-adhesion deficiency-1 revealing elevated activation thresholds in vivo. Clin Dev Immunol. 2012;2012:450738. doi: 10.1155/2012/450738. Epub 2012 Mar 4. PubMed PMID: 22474478; PubMed Central PMCID: PMC3303708.

Moschovakis GL, Förster R. Multifaceted activities of CCR7 regulate T-cell homeostasis in health and disease. Eur J Immunol. 2012 Aug;42(8):1949-55. doi: 10.1002/eji.201242614. Review. PubMed PMID: 22700449.

Moschovakis GL, Bubke A, Dittrich-Breiholz O, Braun A, Prinz I, Kremmer E, Förster R. Deficient CCR7 signaling promotes TH2 polarization and B-cell activation in vivo. Eur J Immunol. 2012 Jan;42(1):48-57. doi: 10.1002/eji.201141753. Epub 2011 Nov 28. PubMed PMID: 21969271.

Koenecke C, Prinz I, Bubke A, Schreder A, Lee CW, Pabst O, Förster R. Shift of graft-versus-host-disease target organ tropism by dietary vitamin A. PLoS One. 2012;7(5):e38252. doi: 10.1371/journal.pone.0038252. Epub 2012 May 30. PubMed PMID: 22666498; PubMed Central PMCID: PMC3364223.

Koenecke C, Lee CW, Thamm K, Föhse L, Schafferus M, Mittrücker HW, Floess S, Huehn J, Ganser A, Förster R, Prinz I. IFN-γ production by allogeneic Foxp3+ regulatory T cells is essential for preventing experimental graft-versus-host disease. J Immunol. 2012 Sep 15;189(6):2890-6. doi: 10.4049/jimmunol.1200413. Epub 2012 Aug 6. PubMed PMID: 22869903.

Kliche S, Worbs T, Wang X, Degen J, Patzak I, Meineke B, Togni M, Moser M, Reinhold A, Kiefer F, Freund C, Förster R, Schraven B. CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules. Blood. 2012 Jan 19;119(3):777-85. doi: 10.1182/blood-2011-06-362269. Epub 2011 Nov 23. PubMed PMID: 22117043.

Haas JD, Ravens S, Düber S, Sandrock I, Oberdörfer L, Kashani E, Chennupati V, Föhse L, Naumann R, Weiss S, Krueger A, Förster R, Prinz I. Development of interleukin-17-producing γδ T cells is restricted to a functional embryonic wave. Immunity. 2012 Jul 27;37(1):48-59. doi: 10.1016/j.immuni.2012.06.003. Epub 2012 Jul 5. PubMed PMID: 22770884.

Girard JP, Moussion C, Förster R. HEVs, lymphatics and homeostatic immune cell trafficking in lymph nodes. Nat Rev Immunol. 2012 Nov;12(11):762-73. doi: 10.1038/nri3298. Epub 2012 Sep 28. Review. PubMed PMID: 23018291.

Förster R, Braun A, Worbs T. Lymph node homing of T cells and dendritic cells via afferent lymphatics. Trends Immunol. 2012 Jun;33(6):271-80. doi: 10.1016/j.it.2012.02.007. Epub 2012 Mar 27. Review. PubMed PMID: 22459312.

Danisch S, Qiu Q, Seth S, Ravens I, Dorsch M, Shibuya A, Shibuya K, Förster R, Bernhardt G. CD226 interaction with CD155 impacts on retention and negative selection of CD8 positive thymocytes as well as T cell differentiation to follicular helper cells in Peyer's Patches. Immunobiology. 2013 Feb;218(2):152-8. doi: 10.1016/j.imbio.2012.02.010. Epub 2012 Feb 17. PubMed PMID: 22429743.

2011:

Fleige H, Haas JD, Stahl FR, Willenzon S, Prinz I.*, Förster R.* Induction of BALT in the absence of IL-17 (Correspondence). Nat Immunol. 2011 Dec 16;13(1):1. doi: 10.1038/ni.2167. PMID: 22179267 * Equal contribution

Wendland M, Willenzon S, Kocks J, Davalos-Misslitz AC, Hammerschmidt SI, Schumann K, Kremmer E, Sixt M, Hoffmeyer A, Pabst O, Förster R.;Lymph node T cell homeostasis relies on steady state homing of dendritic cells.  Immunity. 2011 Dec 23;35(6):945-57. 

Seth S, Qiu Q, Danisch S, Maier MK, Braun A, Ravens I, Czeloth N, Hyde R, Dittrich-Breiholz O, Förster R, Bernhardt G. Intranodal interaction with dendritic cells dynamically regulates surface expression of the co-stimulatory receptor CD226 on murine T Cells. J Biol Chem.2011 Sep 21. [Epub ahead of print]

Braun A, Worbs T, Moschovakis GL, Halle S, Hoffmann K, Bölter J, Münk A, Förster R.; Afferent lymph-derived T cells and DCs use different chemokine receptor CCR7-dependent routes for entry into the lymph node and intranodal migration. Nat Immunol. 2011 Aug 14;12(9):879-87. doi: 10.1038/ni.2085. PMID: 21841786 [PubMed - indexed for MEDLINE] 

Hammerschmidt SI , Friedrichsen M, Boelter J, Lyszkiewicz M, Kremmer E, Pabst O, Förster R Retinoic acid induces homing of protective T and B cells to the gut after subcutaneous immunization in mice. J Clin Invest. 2011 Aug;121(8):3051-61. 

Liu X, Mishra P, Yu S, Beckmann J, Wendland M, Kocks J, Seth S, Hoffmann K, Hoffmann M, Kremmer E, Förster R, Worbs T.  Tolerance induction towards cardiac allografts under costimulation blockade is impaired in CCR7-deficient animals but can be restored by adoptive transfer of syngeneic plasmacytoid dendritic cells. Eur J Immunol. 2011 Mar;41(3):611-23. doi: 10.1002/eji.201040877.  Epub 2011 Feb 10.

Seth S, Ravens I, Lee CW, Glage S, Bleich A, Forster R, Bernhardt G, Koenecke C. (2011). Absence of CD155 aggravates acute graft-versus-host disease. Proc Natl Acad Sci U S A. PMID: 21321238

Hadis U, Wahl B, Schulz O, Hardtke-Wolenski M, Schippers A, Wagner N, Müller W, Sparwasser T, Förster R, Pabst O. Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria. Immunity. 2011 Feb 25;34(2):237-46. Epub 2011 Feb 17.

Marquardt A, Halle S, Seckert CK, Lemmermann NA, Veres TZ, Braun A, Maus UA, Förster R, Reddehase MJ, Messerle M, Busche A. Single cell detection of latent cytomegalovirus reactivation in host tissue. J Gen Virol. 2011 Jun;92(Pt 6):1279-91. Epub 2011 Feb 16.

Seth S, Oberdörfer L, Hyde R, Hoff K, Thies V, Worbs T, Schmitz S, Förster R.CCR7 essentially contributes to the homing of plasmacytoid dendritic cells to lymph nodes under steady-state as well as inflammatory conditions. J Immunol. 2011 Mar 15;186(6):3364-72. Epub 2011 Feb 4.

Föhse L, Suffner J, Suhre K, Wahl B, Lindner C, Lee CW, Schmitz S, Haas JD, Lamprecht S, Koenecke C, Bleich A, Hämmerling GJ, Malissen B, Suerbaum S, Förster R, Prinz I. High TCR diversity ensures optimal function and homeostasis of Foxp3+ regulatory T cells. Eur J Immunol. 2011 Nov;41(11):3101-13. doi: 10.1002/eji.201141986. Epub 2011 Oct 18. PubMed PMID: 21932448.

Haas JD, Nistala K, Petermann F, Saran N, Chennupati V, Schmitz S, Korn T, Wedderburn LR, Förster R, Krueger A, Prinz I. Expression of miRNAs miR-133b and miR-206 in the Il17a/f locus is co-regulated with IL-17 production in αβ and γδ T cells. PLoS One. 2011;6(5):e20171. Epub 2011 May 26. PubMed PMID: 1637854; PubMed Central PMCID: PMC3102691.

Busche A , Schmitz S, Fleige F, Robbins SH, Walzer T, Stewart CA, Forster R, Messerle M, Prinz I Genetic labeling reveals altered turnover and stability of innate lymphocytes in latent mouse cytomegalovirus infection J Immunol. 2011 in press.

2010

Bakocevic, N., Worbs, T., Davalos-Misslitz, A., and Forster, R. (2010). T cell-dendritic cell interaction dynamics during the induction of respiratory tolerance and immunity. J Immunol 184, 1317-1327.

Chennupati, V., Worbs, T., Liu, X., Malinarich, F. H., Schmitz, S., Haas, J. D., Malissen, B., Forster, R., and Prinz, I. (2010). Intra- and intercompartmental movement of gammadelta T cells: intestinal intraepithelial and peripheral gammadelta T cells represent exclusive nonoverlapping populations with distinct migration characteristics. J Immunol 185, 5160-5168. 

Del Rio, M. L., Bernhardt, G., Rodriguez-Barbosa, J. I., and Forster, R. (2010). Development and functional specialization of CD103(+) dendritic cells. Immunol Rev 234, 268-281.

Krueger, A., Willenzon, S., Lyszkiewicz, M., Kremmer, E., and Forster, R. (2010). CC chemokine receptor (CCR) 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus. Blood 115:1906-1912.

Luchtefeld, M., Grothusen, C., Gagalick, A., Jagavelu, K., Schuett, H., Tietge, U. J., Pabst, O., Grote, K., Drexler, H., Forster, R., and Schieffer, B. (2010). Chemokine receptor 7 knockout attenuates atherosclerotic plaque development. Circulation 122, 1621-1628.

Malinarich, F. H., Grabski, E., Worbs, T., Chennupati, V., Haas, J. D., Schmitz, S., Candia, E., Quera, R., Malissen, B., Forster, R., et al. (2010). Constant TCR triggering suggests that the TCR expressed on intestinal intraepithelial gammadelta T cells is functional in vivo. Eur J Immunol 40, 3378-3388.

Qiu, Q., Ravens, I., Seth, S., Rathinasamy, A., Maier, M. K., Davalos-Misslitz, A., Forster, R., and Bernhardt, G. (2010). CD155 is involved in negative selection and is required to retain terminally maturing CD8 T cells in thymus. J Immunol 184, 1681-1689.

Rathinasamy, A., Czeloth, N., Pabst, O., Forster, R., and Bernhardt, G. (2010). The origin and maturity of dendritic cells determine the pattern of sphingosine 1-phosphate receptors expressed and required for efficient migration. J Immunol 185, 4072-4081.

Schumann, K., Lammermann, T., Bruckner, M., Legler, D. F., Polleux, J., Spatz, J. P., Schuler, G., Forster, R., Lutz, M. B., Sorokin, L., and Sixt, M. (2010). Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells. Immunity 32, 703-713.

2009

Carlens, J., Wahl, B., Ballmaier, M., Bulfone-Paus, S., Forster, R., and Pabst, O. (2009). Common gamma-chain-dependent signals confer selective survival of eosinophils in the murine small intestine. J Immunol 183, 5600-5607.

Ensminger, S. M., Abele-Ohl, S., Ohl, L., Spriewald, B. M., Ramsperger-Gleixner, M., Weyand, M., and Forster, R. (2009). Unaltered levels of transplant arteriosclerosis in the absence of the B cell homing chemokine receptor CXCR5. Transpl Immunol 20, 218-223.

Haas, J. D., Gonzalez, F. H., Schmitz, S., Chennupati, V., Fohse, L., Kremmer, E., Forster, R., and Prinz, I. (2009). CCR6 and NK1.1 distinguish between IL-17A and IFN-gamma-producing gammadelta effector T cells. Eur J Immunol 39, 3488-3497.

Halle, S., Dujardin, H. C., Bakocevic, N., Fleige, H., Danzer, H., Willenzon, S., Suezer, Y., Hammerling, G., Garbi, N., Sutter, G., et al. (2009). Induced bronchus-associated lymphoid tissue serves as a general priming site for T cells and is maintained by dendritic cells. J Exp Med 206, 2593-2601.

Kocks, J. R., Adler, H., Danzer, H., Hoffmann, K., Jonigk, D., Lehmann, U., and Forster, R. (2009). Chemokine receptor CCR7 contributes to a rapid and efficient clearance of lytic murine gamma-herpes virus 68 from the lung, whereas bronchus-associated lymphoid tissue harbors virus during latency. J Immunol 182, 6861-6869.

Koenecke, C., Chennupati, V., Schmitz, S., Malissen, B., Forster, R., and Prinz, I. (2009a). In vivo application of mAb directed against the gammadelta TCR does not deplete but generates "invisible" gammadelta T cells. Eur J Immunol 39, 372-379.

Koenecke, C., Czeloth, N., Bubke, A., Schmitz, S., Kissenpfennig, A., Malissen, B., Huehn, J., Ganser, A., Forster, R., and Prinz, I. (2009b). Alloantigen-specific de novo induced Foxp3(+) Treg revert in vivo and do not protect from experimental GvHD. Eur J Immunol 39, 3091-3096.

Koenecke, C., and Forster, R. (2009). CCR9 and inflammatory bowel disease. Expert Opin Ther Targets 13, 297-306.

Krege, J., Seth, S., Hardtke, S., Davalos-Misslitz, A. C., and Forster, R. (2009). Antigen-dependent rescue of nose-associated lymphoid tissue (NALT) development independent of LTbetaR and CXCR5 signaling. Eur J Immunol 39, 2765-2778.

Molenaar, R., Greuter, M., van der Marel, A. P., Roozendaal, R., Martin, S. F., Edele, F., Huehn, J., Forster, R., O'Toole, T., Jansen, W., et al. (2009). Lymph node stromal cells support dendritic cell-induced gut-homing of T cells. J Immunol 183, 6395-6402.

Quast, T., Tappertzhofen, B., Schild, C., Grell, J., Czeloth, N., Forster, R., Alon, R., Fraemohs, L., Dreck, K., Weber, C., et al. (2009). Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells. Blood 113, 5801-5810.

Seth, S., Ravens, I., Kremmer, E., Maier, M. K., Hadis, U., Hardtke, S., Forster, R., and Bernhardt, G. (2009). Abundance of follicular helper T cells in Peyer's Patches is modulated by CD155. Eur J Immunol.

Velaga, S., Herbrand, H., Friedrichsen, M., Jiong, T., Dorsch, M., Hoffmann, M. W., Forster, R., and Pabst, O. (2009). Chemokine receptor CXCR5 supports solitary intestinal lymphoid tissue formation, B cell homing, and induction of intestinal IgA responses. J Immunol 182, 2610-2619.

Voedisch, S., Koenecke, C., David, S., Herbrand, H., Forster, R., Rhen, M., and Pabst, O. (2009). Mesenteric lymph nodes confine dendritic cell-mediated dissemination of Salmonella enterica serovar Typhimurium and limit systemic disease in mice. Infect Immun 77, 3170-3180.

Worbs, T., and Forster, R. (2009). T cell migration dynamics within lymph nodes during steady state: an overview of extracellular and intracellular factors influencing the basal intranodal T cell motility. Curr Top Microbiol Immunol 334, 71-105.

2008

Berberich, S., Dahne, S., Schippers, A., Peters, T., Muller, W., Kremmer, E., Forster, R., and Pabst, O. (2008). Differential molecular and anatomical basis for B cell migration into the peritoneal cavity and omental milky spots. J Immunol 180, 2196-2203.

del Rio, M. L., Rodriguez-Barbosa, J. I., Bolter, J., Ballmaier, M., Dittrich-Breiholz, O., Kracht, M., Jung, S., and Forster, R. (2008). CX3CR1+ c-kit+ bone marrow cells give rise to CD103+ and CD103- dendritic cells with distinct functional properties. J Immunol 181, 6178-6188.

Ellinghaus, U., Rupec, R. A., Pabst, O., Ignatius, R., Forster, R., Dorken, B., and Jundt, F. (2008). IkappaBalpha is required for marginal zone B cell lineage development. Eur J Immunol 38, 2096-2105.

Ensminger, S. M., Helm, S. N., Ohl, L., Spriewald, B. M., Abele, S., Wollin, M., Wood, K. J., Weyand, M., and Forster, R. (2008). Increased transplant arteriosclerosis in the absence of CCR7 is associated with reduced expression of Foxp3. Transplantation 86, 590-600.

Forster, R., Davalos-Misslitz, A., and Rot, A. (2008a). CCR7 and its ligands: Balancing Immunity and Tolerance. Nature Rev Immunol 8, 362-371.

Forster, R., Pabst, O., and Bernhardt, G. (2008b). Homeostatic chemokines in development, plasticity, and functional organization of the intestinal immune system Seminar Immunol 21 April 2008 epub ahead of print.

Hammerschmidt, S. I., Ahrendt, M., Bode, U., Wahl, B., Kremmer, E., Forster, R., and Pabst, O. (2008). Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo. J Exp Med 205, 2483-2490.

Herbrand, H., Bernhardt, G., Forster, R., and Pabst, O. (2008). Dynamics and function of solitary intestinal lymphoid tissue. Crit Rev Immunol 28, 1-13.

Lämmermann, T., Bader, B., Monkley, S., Tim Worbs, Wedlich-Soldner, R., Hirsch, K., Keller, M., Forster, R., Critchley, D., Fassler, R., and Sixt, M. (2008). Rapid leukocyte migration by integrin-independent flowing and squeezing. Nature 453, 51-55.

Wendland, M., Kocks, J. R., Davalos-Misslitz, A., Willenzon, S., Hoffmeyer, A., Pabst, O., and R., F. (2008). A CCR7-dependent steady state homing of dendritic cells essentially required for lymph node T cell homeostasis. to be submitted within the next 2 weeks.

Worbs, T., Bernhardt, G., and Forster, R. (2008). Factors governing the intranodal migration behavior of T lymphocytes. Immunol Rev 221, 44-63.

2007

Berberich, S., Forster, R., and Pabst, O. (2007). The peritoneal micromilieu commits B cells to home to body cavities and the small intestine. Blood 109, 4627-4634.

Czeloth, N., Schippers, A., Wagner, N., Muller, W., Kuster, B., Bernhardt, G., and Forster, R. (2007). Sphingosine-1 phosphate signaling regulates positioning of dendritic cells within the spleen. J Immunol 179, 5855-5863.

Davalos-Misslitz, A. C., Rieckenberg, J., Willenzon, S., Worbs, T., Kremmer, E., Bernhardt, G., and Forster, R. (2007a). Generalized multi-organ autoimmunity in CCR7-deficient mice. Eur J Immunol 37, 613-622.

Davalos-Misslitz, A. C., Worbs, T., Willenzon, S., Bernhardt, G., and Forster, R. (2007b). Impaired responsiveness to TCR stimulation and defective negative selection of thymocytes in CCR7-deficient mice. Blood 110, 4351-4359.

del Rio, M. L., Pabst, O., Ramirez, P., Penuelas-Rivas, G., Forster, R., and Rodriguez-Barbosa, J. I. (2007a). The thymus is required for the ability of FTY720 to prolong skin allograft survival across different histocompatibility MHC barriers. Transpl Int 20, 895-903.

del Rio, M. L., Rodriguez-Barbosa, J. I., Kremmer, E., and Forster, R. (2007b). CD103- and CD103+ bronchial lymph node dendritic cells are specialized in presenting and cross-presenting innocuous antigen to CD4+ and CD8+ T cells. J Immunol 178, 6861-6866.

Forster, R. (2007). [Chemokine-dependent development of primary, secondary and tertiary lymphoid organs]. Verh Dtsch Ges Pathol 91, 87-90.

Halle, S., Bumann, D., Herbrand, H., Willer, Y., Dahne, S., Forster, R., and Pabst, O. (2007). Solitary intestinal lymphoid tissue provides a productive port of entry for Salmonella enterica serovar Typhimurium. Infect Immun 75, 1577-1585.

Kahlmann, D., Davalos-Misslitz, A. C., Ohl, L., Stanke, F., Witte, T., and Forster, R. (2007). Genetic variants of chemokine receptor CCR7 in patients with systemic lupus erythematosus, Sjogren's syndrome and systemic sclerosis. BMC Genet 8, 33.

Kocks, J. R., Davalos-Misslitz, A. C., Hintzen, G., Ohl, L., and Forster, R. (2007). Regulatory T cells interfere with the development of bronchus-associated lymphoid tissue. J Exp Med 204, 723-734.

Maier, M. K., Seth, S., Czeloth, N., Qiu, Q., Ravens, I., Kremmer, E., Ebel, M., Muller, W., Pabst, O., Forster, R., and Bernhardt, G. (2007). The adhesion receptor CD155 determines the magnitude of humoral immune responses against orally ingested antigens. Eur J Immunol 37, 2214-2225.

Pabst, O., Bernhardt, G., and Forster, R. (2007). The impact of cell-bound antigen transport on mucosal tolerance induction. J Leukoc Biol 82, 795-800.

Scandella, E., Fink, K., Junt, T., Senn, B. M., Lattmann, E., Forster, R., Hengartner, H., and Ludewig, B. (2007). Dendritic cell-independent B cell activation during acute virus infection: a role for early CCR7-driven B-T helper cell collaboration. J Immunol 178, 1468-1476.

Seth, S., Maier, M. K., Qiu, Q., Ravens, I., Kremmer, E., Forster, R., and Bernhardt, G. (2007). The murine pan T cell marker CD96 is an adhesion receptor for CD155 and nectin-1. Biochem Biophys Res Commun 364, 959-965.

Tian, J., Pabst, O., Romermann, D., Skubich, S., Forster, R., Beckmann, J., Chen, J. H., and Hoffmann, M. W. (2007). Inactivation of T-cell receptor-mediated integrin activation prolongs allograft survival in ADAP-deficient mice. Transplantation 84, 400-406.

Wendland, M., Czeloth, N., Mach, N., Malissen, B., Kremmer, E., Pabst, O., and Forster, R. (2007). CCR9 is a homing receptor for plasmacytoid dendritic cells to the small intestine. Proc Natl Acad Sci U S A 104, 6347-6352.

Worbs, T., and Forster, R. (2007). A key role for CCR7 in establishing central and peripheral tolerance. Trends Immunol 28, 274-280.

Worbs, T., Mempel, T. R., Bolter, J., von Andrian, U. H., and Forster, R. (2007). CCR7 ligands stimulate the intranodal motility of T lymphocytes in vivo. J Exp Med 204, 489-495.

Ziegler, E., Oberbarnscheidt, M., Bulfone-Paus, S., Forster, R., Kunzendorf, U., and Krautwald, S. (2007). CCR7 signaling inhibits T cell proliferation. J Immunol 179, 6485-6493.

2006

Hintzen, G., Ohl, L., del Rio, M. L., Rodriguez-Barbosa, J. I., Pabst, O., Kocks, J. R., Krege, J., Hardtke, S., and Forster, R. (2006). Induction of tolerance to innocuous inhaled antigen relies on a CCR7-dependent dendritic cell-mediated antigen transport to the bronchial lymph node. J Immunol 177, 7346-7354.

Kamphuis, E., Junt, T., Waibler, Z., Forster, R., and Kalinke, U. (2006). Type I interferons directly regulate lymphocyte recirculation and cause transient blood lymphopenia. Blood 108, 3253-3261.

Lee, B. P., Chen, W., Shi, H., Der, S. D., Forster, R., and Zhang, L. (2006). CXCR5/CXCL13 interaction is important for double-negative regulatory T cell homing to cardiac allografts. J Immunol 176, 5276-5283.

Misslitz, A., Bernhardt, G., and Forster, R. (2006). Trafficking on serpentines: molecular insight on how maturating T cells find their winding paths in the thymus. Immunol Rev 209, 115-128.

Pabst, O., Herbrand, H., Willenzon, S., Worbs, T., Schippers, A., Muller, W., Bernhardt, G., and Forster, R. (2006). Enhanced FTY720-mediated lymphocyte homing requires G alpha i signaling and depends on beta 2 and beta 7 integrin. J Immunol 176, 1474-1480.

Worbs, T., Bode, U., Yan, S., Hoffmann, M. W., Hintzen, G., Bernhardt, G., Forster, R., and Pabst, O. (2006). Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells. J Exp Med 203, 519-527.

2005

Czeloth, N., Bernhardt, G., Hofmann, F., Genth, H., and Forster, R. (2005). Sphingosine-1-phosphate mediates migration of mature dendritic cells. J Immunol 175, 2960-2967.

Dudda, J. C., Lembo, A., Bachtanian, E., Huehn, J., Siewert, C., Hamann, A., Kremmer, E., Forster, R., and Martin, S. F. (2005). Dendritic cells govern induction and reprogramming of polarized tissue-selective homing receptor patterns of T cells: important roles for soluble factors and tissue microenvironments. Eur J Immunol 35, 1056-1065.

Gunther, K., Leier, J., Henning, G., Dimmler, A., Weissbach, R., Hohenberger, W., and Forster, R. (2005). Prediction of lymph node metastasis in colorectal carcinoma by expressionof chemokine receptor CCR7. Int J Cancer.

Hardtke, S., Ohl, L., and Forster, R. (2005). Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B cell help. Blood 106, 1924-1931.

Johansson-Lindbom, B., Svensson, M., Pabst, O., Palmqvist, C., Marquez, G., Forster, R., and Agace, W. W. (2005). Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing. J Exp Med 202, 1063-1073.

Junt, T., Fink, K., Forster, R., Senn, B., Lipp, M., Muramatsu, M., Zinkernagel, R. M., Ludewig, B., and Hengartner, H. (2005). CXCR5-dependent seeding of follicular niches by B and Th cells augments antiviral B cell responses. J Immunol 175, 7109-7116.

Pabst, O., Herbrand, H., Worbs, T., Friedrichsen, M., Yan, S., Hoffmann, M. W., Korner, H., Bernhardt, G., Pabst, R., and Forster, R. (2005a). Cryptopatches and isolated lymphoid follicles: dynamic lymphoid tissues dispensable for the generation of intraepithelial lymphocytes. Eur J Immunol 35, 98-107.

Pabst, O., Peters, T., Czeloth, N., Bernhardt, G., Scharffetter-Kochanek, K., and Forster, R. (2005b). Cutting Edge: Egress of Newly Generated Plasma Cells from Peripheral Lymph Nodes Depends on {beta}2 Integrin. J Immunol 174, 7492-7495.

Strobel, P., Marino, M., Feuchtenberger, M., Rouziere, A. S., Tony, H. P., Wulbrand, U., Forster, R., Zettl, A., Lee Harris, N., Kreipe, H., et al. (2005). Micronodular thymoma: an epithelial tumour with abnormal chemokine expression setting the stage for lymphoma development. J Pathol.

Viebig, N. K., Wulbrand, U., Forster, R., Andrews, K. T., Lanzer, M., and Knolle, P. A. (2005). Direct activation of human endothelial cells by Plasmodium falciparum-infected erythrocytes. Infect Immun 73, 3271-3277.

Yan, S., Rodriguez-Barbosa, J. I., Pabst, O., Beckmann, J. H., Brinkmann, V., Forster, R., and Hoffmann, M. W. (2005a). Control of intestinal allograft rejection by FTY720 and costimulation blockade. Transplant Proc 37, 114-115.

Yan, S., Rodriguez-Barbosa, J. I., Pabst, O., Beckmann, J. H., Brinkmann, V., Forster, R., and Hoffmann, M. W. (2005b). Protection of Mouse Small Bowel Allografts by FTY720 and Costimulation Blockade. Transplantation 79, 1703-1710.