Collaborative and infrastructure projects
The life scientists at the MHH are currently involved in eleven collaborative and infrastructure projects in the current EU Framework Programme for Research and Innovation "Horizon Europe" and 22 projects in the predecessor programme Horizon 2020.
Collaborative projects with coordination at the MHH
D-SOLVE
Understanding the individual host response against Hepatitis D Virus to develop a personalized approach
for the management of hepatitis D
Coordinator: Prof. Dr. Heiner Wedemeyer, Clinic for Gastroenterology, Hepatology and Endocrinology
Duration: 01.10.2022 – 30.09.2026
Targeting cardiac fibrosis with next generation RNA therapeutics
Coordinator: Prof. Dr. Dr. Thomas Thum, Institute for Molecular and Translational Therapeutic Strategies
Duration: 01.08.2022 – 31.05.2024
HLA-homozygous iPSC-cardiomyocytE Aggregate manufacturing technoLogies for allogenic cell therapy to the heart
Coordinator: Dr. Robert Zweigerdt, Clinic for Cardiac, Thoracic, Transplantation and Vascular Surgery
Duration: 01.09.2022 – 28.02.2026
Residual disease assessment in hematologic malignancies to improve patient-relevant outcomes across Europe
Coordinator: Prof. Dr. Michael Heuser, Clinic for Haematology, Haemostaseology, Oncology and Stem Cell Transplantation
Duration: 01.04.204 - 31.03.2029
Collaborative projects with participation of the MHH
AAVolution (EIC-Pathfinder Project)
Next-generation AAV vectors for liver-directed gene therapy
Partner: Prof. Dr. Hildegard Büning, Institute for Experimental Haematology
Duration: 01.10.2022 – 30.09.2026
Hyper-targeting CAR NK cells from induced pluripotent stem cells for novel off-the-shelf anti-tumor therapies
Partner: Prof. Dr. Axel Schambach, Institute for Experimental Haematology
Duration: 01.04.2023 – 31.03.2026
Master Framework and Pragmatic Clinical Trial for Relapse or Refractory Acute Myeloid Leukemia
Partner: Prof. Dr. Michael Heuser, Clinic for Haematology, Haemostaseology, Oncology and Stem Cell Transplantation
Duration: 01.04.2023 - 31.03.2028
International Study for Treatment of Childhood Relapsed ALL 2020
Partner: Dr. Martin Zimmermann, Clinic for Paediatric Haematology and Oncology
Duration: 01.05.20123 - 30.04.2028
Next-generation models and genetic therapies for rare neuromuscular diseases
Partner: Prof. Dr. Hildegard Büning, Institute for Experimental Haematology
Duration: 01.06.2023 - 31.05.2027
Towards large -scale adaption and tailored implementation of evidence-based primary cancer prevention programmes in Europe and beyond
Partner: Prof. Dr. Heiner Wedemeyer, Clinic for Gastroenterology, Hepatology, Infectiology and Endocrinology;
Prof. Dr Uwe Tegtbur, Rehabilitation and Sports Medicine
Duration: 01.06.2023 - 31.05.2027
ProtAct-Us from long-term consequences of road crashes
Partner: Dr. Heiko Johannsen, Clinic for Trauma Surgery, Trauma Research
Duration: 01.06.2024 - 31.05.2027
Reconstruction and Computational Modelling for Inherited Metabolic Diseases
Partner: Prof. Dr. Anibh Das, Clinic for Paediatric Kidney, Liver and Metabolic Diseases
Duration: 01.06.2023 - 31.05.2027
Collaborative projects with coordination at the MHH
ARISE
Aortic Valve Replacement using Individualised Regenerative Allografts: Bridging the Therapeutic Gap
Coordinator: Dr. Samir Sarikouch, Clinic for Cardiac, Thoracic, Transplantation and Vascular Surgery
Duration: 01.01.2015 - 30.03.2019
Tools and TECHNOlogies for Breakthrough in hEArt Therapies
Coordinator: Dr. Robert Zweigerdt, Clinic for Cardiac, Thoracic, Transplantation and Vascular Surgery of the MHH / LEBAO - Leibniz Research Laboratories for Biotechnology and Artificial Organs
Duration: 01.01.2016 - 31.12.2019
Collaborative projects with participation of the MHH
3TR (IMI-Project)
Identification of the Molecular Mechanisms of non-response to Treatments, Relapses and Remission in Autoimmune, Inflammatory, and Allergic Conditions
Partner: Prof. Dr. Torsten Witte, Clinic for Rheumatology and Immunology
Duration: 01.09.2019 - 31.08.2026
Aerodynamic and Flexible Trucks for Next Generation of Long Distance Road Transport
Partner: Dr. Heiko Johannsen, Clinic for Trauma Surgery
Duration: 01.10.2017 - 31.09.2021
Action Leveraging Evidence to Reduce perinatal morTality and morbidity in sub-Saharan Africa
Partner: Prof. Dr. Mechthild Groß, Clinic for Gynaecology and Obstetrics
Duration: 01.01.2020 - 31.12.2024
Development of Next-Generation Gene Therapies for Cardiovascular Disease
Partner: Prof. Dr. Dr. Thomas Thum, Institute for Molecular and Translational Therapeutic Strategies
Duration: 01.01.2019 - 30.06.2024
Adeno-Associated Virus Vector-Mediated Liver Gene Therapy for Crigler-Najjar Syndrome
Partner: Prof. Dr.Ulrich Baumann, Clinic for Paediatric Kidney, Liver and Metabolic Diseases;
Dr. Michael Ott, Clinic for Gastroenterology, Hepotology and Endocrinology
Duration: 01.01.2018 - 30.06.2023
European-Latin American network for the assessment of biomarkers to predict and diagnose hepatobiliary malignancies and characterization of risk factors for cancer development
Partner: Prof. Dr. Arndt Vogel, Clinic for Gastroenterology, Hepotology and Endocrinology
Duration: 01.01.2019 - 31.12.2023
HARMONIzation and integrative analysis of regional, national and international Cohorts on primary Sjögren’s Syndrome (pSS) towards improved stratification, treatment and health policy making
Partner: Prof. Dr. Torsten Witte, Clinic for Rheumatology and Immunology
Duration: 01.01.2017 - 30.12.2020
Immune Safety Avatar: nonclinical mimicking of the immune system effects of immunmodulatory therapies
Partner: Prof. Dr. Thomas Illig, Hanover Unified Biobank und Prof. Dr. Danny Jonigk, Institute of Pathology
Duration: 01.12.2019 - 30.11.2025
Screening for liver fibrosis - population-based study across European countries
Partner: Prof. Dr. Frank Lammert, Vice President and member of the Board of Directors responsible for healthcare;
Prof. Dr. Heiner Wedemeyer, Clinic for Gastroenterology, Hepatology and Endocrinology
Duration: 01.01.2020 - 30.05.2025
Medical Device Obligations Taskforce
Partner: Prof. Dr. Theodor Doll, Clinic for Ear, Nose and Throat Medicine
Duration: 01.01.2019 - 31.12.2023
Fostering Palliative Care of Adults and Children with Cancer through Advanced Patient Reported Outcome Systems
Partner: Dr. Annette Sander, Clinic for Paediatrics, Paediatric Haematology and Oncology
Duration: 01.01.2019 - 30.12.2022
Stem-cell based gene therapy for recombination deficient SCID
Partner: Prof. Dr. Axel Schambach, Institute for Experimental Haematology
Duration: 01.01.2018 - 31.12.2022
An in silico-based approach to improve the efficacy and precision of drug REPurpOsing TRIALs for a mechanism-based patient cohort with predominant cerebro-cardiovascular phenotypes
Partner: Prof. Dr. Johann Bauersachs, Clinic for Cardiology and Angiology
Duration: 01.02.2018 - 31.01.2024
Reshaping undesired Inflammation in challenged Tissue Homeostasis by Next-Generation regulatory T cell (Treg) Approaches – from Advanced Technology Developments to First-in-Human Trials
Partner: Dr. Elmar Jäckel and PD Dr. Matthias Hardtke-Wolenski - Clinic for Gastroenterology, Hepotology and Endocrinology
Duration: 01.01.2019 - 31.12.2023
heaRt failurE paTient managEment and iNTerventIOns usiNg continuous patient monitoring outside hospitals and real
world data
Partner: Prof. Dr. Arjang Ruhparwar und DP Dr. Bastian Schmack, Clinic for Cardiac, Thoracic, Transplantation and Vascular Surgery
Duration: 01.05.2021 - 30.04.2025
Safety CaUsation, Benefits and Efficiency
Partner: Dr. Heiko Johannsen, Clinic for Trauma Surgery
Duration: 01.05.2015 - 30.04.2018
DevelopIng Genetic medicines for Severe Combined Immunodeficiency (SCID)
Partner: Prof. Dr. Axel Schambach, Institute for Experimental Haematology
Duration: 01.01.2016 - 31.12.2019
Synergy-based Open-source Foundations and Technologies for Prosthetics and Rehabilitation
Partner: Dr. Eike Jakubowitz, Clinic for Orthopaedics
Duration: 01.03.2016 - 29.02.2020
A therapeutic vaccine to cure Hepatitis B
Partner: Prof. Dr. Markus Cornberg, Clinic for Gastroenterology, Hepatology and Endocrinology
Duration: 01.01.2020 - 31.12.2024
Infrastructure projects
INFRAFRONTIER2020
Towards enduring mouse resources and services advancing research into human health and disease
Partner: Prof. Dr. André Bleich, Institute of Laboratory Animal Science and Central Animal Laboratory
Duration: 01.01.2017 - 31.12.2021
Widening Participation
Twinning Projects
NanoMedTwinPromoting smart specialization at the Technical University of Moldova by developing the field of Novel Nanomaterials for BioMedical Applications through excellence in research and twinning
Partner: Dr. Serghei Cebotari, Clinic for Cardiac, Thoracic, Transplantation and Vascular Surgery
Duration: 01.11.2018 - 31.10.2022
Contact
Overview of our contact persons