Di Donato N, NMA Consortium, Thom A, Rump A, Greve JN, Kropp M, Cadiñanos J, Calabro S, Cathey S, Chung B, Cope H, Costales M, Cuvertino S, Dinkel P, Erripi K, Fry AE, Garavelli L, Guan K, Hoffjan S, Janzarik WG, Koenig M, Kreimer I, Kuenzel K, Mancini G, Marin-Reina P, Meinhardt A, Niehaus I, Pilz D, Ricca I, Simarro FS, Schrock E, Marquardt A, Taft MH, Tezcan K, Thunström S, Verhagen J, Verloes A, Wollnik B, Krawitz P, Hsieh T-C, Zeef L, Seifert M, Heide M, Lawrence CB, Roberts N, Manstein DJ, Woolf AS, Banka S

Genomic and biological panoramas of non-muscle actinopathies. Preprint Medarxiv, 2024.

 

Hecquet T, Arbogast N, Suhner D, Goetz A, Amann G, Yürekli S, Marangoni F, Greve JN, Di Donato N, Reymann AC

Classification of human actin pathological variants using C. elegans CRISPR-generated models. Preprint Bioarxiv, 2024.

https://doi.org/10.1101/2024.07.22.604239

Greve JN*, Manstein DJ*

Baraitser-Winter Syndrome Hotspot Mutation R196H in Cytoskeletal β-actin Reduces F-actin Stability and Perturbs Interaction with the Arp2/3 Complex. Preprint Bioarxiv, 2024. doi.org/10.1101/2024.03.20.585892

*co-corresponding authors

 

Kengyel A*, Palarz PM*, Krohn J, Marquardt A, Greve JN, Heiringhoff R, Jörns A, Manstein DJ.

Motor Properties of Myosin 5C Are Modulated by Tropomyosin Isoforms and Inhibited by Pentabromopseudilin. Frontiers in Physiology, 2024. doi.org/10.3389/fphys.2024.1394040

*contributed equally

 

Greve JN,* Schwäbe FV*, Taft MH, Manstein DJ.

Biochemical Characterization of cardiac α-actin Mutations A21V and D26N Implicated in Hypertrophic Cardiomyopathy. Cytoskeleton, 2024.

*contributed equally

 

Greve JN, Marquardt A, Heiringhoff R, Reindl T, Thiel C, Di Donato N, Taft MH, Manstein DJ. The non–muscle actinopathy–associated mutation E334Q in cytoskeletal γ–actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins. eLife, 2023. doi.org/10.7554/eLife.93013.1

 

Reindl T*, Giese S*, Greve JN, Reinke PY, Chizhov I, Latham SL, Mulvihill DP, Taft MH, Manstein DJ.

Distinct actin-tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes. iScience, 2022. doi.org/10.1016/j.isci.2022.104484

*contributed equally

 

Greve JN, Schwäbe FV, Pokrant T, Faix J, Di Donato N, Taft MH, Manstein DJ.

Frameshift mutation S368fs in the gene encoding cytoskeletal β-actin leads to ACTB-associated syndromic thrombocytopenia by impairing actin dynamics. European Journal of Cell Biology, 2022. doi.org/10.1016/j.ejcb.2022.151216

 

Pertici I*, Taft MH*, Greve JN, Fedorov R, Caremani M, Manstein DJ.

Allosteric modulation of cardiac myosin mechanics and kinetics by the conjugated omega-7,9 trans-fat rumenic acid. Journal of Physiology, 2021. doi.org/10.1113/JP281563

*contributed equally