Projekte

Themenbereiche

Die Inhalte der angebotenen DigiStrucMed-Projekte lassen sich in vier Themenkomplexe hinsichtlich ihrer Anwendungsgebiete/Zielsetzungen einteilen:

  1. Werkzeuge und Technologien für Ärzte. Digitalisierungsprozesse in der Medizin, wie z.B. elektronische Anamnesetools, die Einführung der strukturierten Datenerfassung oder die digitale Kommunikation in Studien mit den analogen Prozessen sollen verglichen oder neuartige Methoden entwickelt werden zur Auswertung gesundheitsrelevanter Daten. Außerdem sollen durch die Vernetzung bereits digitalisierter Daten und auf Basis geeigneter Algorithmen Entscheidungsunterstützungssysteme entwickelt bzw. evaluiert werden.
  2. Werkzeuge und Technologien für Patienten: Projekte des zweiten Themenkomplexes beschäftigen sich mit der Entwicklung von Technologien, die die Patienten dabei fördern sollen, informierte Entscheidungen treffen zu können (informierter Patient) sowie in einem zweiten Schwerpunkt Technologien, die die Nachbeobachtung der Patienten vereinfachen und z. B. Heim-Monitoring ermöglichen sollen.
  3. Analysetechnologien für Diagnostik und Behandlung: Analysetechnologien für die Labor- und bildgebende Diagnostik, aber auch zur Prädiktion von Therapieeffektivität und -resistenz, werden zur Verlaufsbeurteilung und zur Prävention entwickelt und evaluiert. Diese können beispielsweise mit Verfahren künstlicher Intelligenz realisiert werden (z.B. Bildanalysen auf Basis Neuronaler Netzwerke) oder den Schwerpunkt auf Big Data, Datenbanken und Data-Mining legen.
  4. Robotik und Assistenzsysteme: Es werden die Einsatzmöglichkeiten von Roboter- und Assistenzsystemen in Klinik und Pflege untersucht.

 

5. Jahrgang 2025/26

Die folgende Tabelle gibt eine Übersicht über die den Studierenden im 5. Jahrgang 2025/26 angebotenen Projekte (vorläufig zugelassene Projekte):

ID

Title

Project leader Medicine

Project Leader Informatics

B01

Development of a bioinformatical tool to predict clinical responses to CFTR modulator therapy by integrating microbial metagenomics, inflammatory cell transcriptomics and secretomics

Prof. Dr. med. Anna-Maria Dittrich

Pediatric Pneumology, Allergy and Neonatology, Hannover Medical School

Prof. Dr. Dipl.-Ing. Wolfgang Nejdl

Institute of Data Science, L3S Research Institute, Leibniz University Hannover

B02

Automation of ISHAK Scoring: Machine Based Development of Unsupervised Liver Fibrosis Index

PD Dr. Nagoud Schukfeh

Department of Pediatric Surgery, Hannover Medical School

Prof. Dr.-Ing. Andrea Schenk

Fraunhofer Institute for Digital Medicine MEVIS

B03

Functional profiling of the respiratory tract microbiome in severe asthma patients and healthy individuals

Prof. Dr. med. Hortense Slevogt

Department of Pneumology and Infectiology, Hannover Medical School

Prof. Dr. Yang Li

Computational Biology for Individualised Medicin, Centre for Individualised Infection Medicine (CiiM), Helmholtz Centre for Infection Research & Hannover Medical School

B04

Exploring Client-Centered and Clinical Psychotherapy Programs Using the LeA+ Digital Therapist in Psychocardiology

Prof. Dr. med. Kai G. Kahl

Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School

Prof. Dr. rer. nat. habil. Michael H. Breitner

Information Systems and Management Institute, Leibniz Universität Hannover

B05

Accelerated Ventilation / Perfusion (V/Q) Scan of the human Lung with Phase-Resolved Functional Lung (PREFUL) MRI by means of parallel Imaging using GRAPPA-Net

Prof. Dr. med. Jens Vogel-Claussen

Institute of Diagnostic and Interventional Radiology, Hannover Medical School

Andreas Voskrebenzev, Ph.D.

Institute of Diagnostic and Interventional Radiology, Hannover Medical School

B06

Large Language Modelle zur Unterstützung von Patientinnen mit erblichen Brust- und Eierstockkrebs: Meinungsforschung, Entwicklung von Qualitätsstandards und Implementierung in einer mobilen App

Dr. rer. nat. Beate Vajen

Department of Human Genetics, Hannover Medical School

Dr. rer. nat. Dominik Wolff

Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School

B07

Prevention of postoperative delirium by the use of PARO

PD Dr. med. Hans Worthmann

Department of Neurology, Hannover Medical School

Prof. Dr.-Ing. Hanno Homann

Faculty I - Electrical Engineering and Information Technology,  Hannover University of Applied Sciences

B08

Structured Digital Learning and AI Optimization for Heart Failure Education

Prof. Dr. med. David Duncker

Hannover Heart Rhythm Center, Department of Cardiology and Angiology, Hannover Medical School

Prof. Dr. Maria-Esther Vidal

Data Science Institute, Leibniz University of Hannover

B09

Analysis of broad interdisciplinary data sets from patients with transthyretin amyloidosis by classical statistical and advanced machine-learning methods for improved prediction of disease progression and outcomes

Prof. Dr. med. Udo Bavendiek

Department of Cardiology and Angiology, Hannover Medical School

Amyloidosis Centre Lower Saxony, Hannover Medical School

Dr. Matthias Gietzelt

Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School

B10

Vision-Based Gait Analysis for Parkinson's Disease: Differential Diagnosis and Progression Monitoring (compared to multiple sclerosis, myasthenia gravis and healthy controls)

Prof. Dr. med. Aiden Haghikia

Clinic of Neurology with Clinical Neurophysiology, Hannover Medical School

Prof. Dr.-Ing. Hanno Homann

Faculty I - Electrical Engineering and Information Technology,  Hannover University of Applied Sciences

B11

CLARA - Cognitive Language Assistant and Retrieval Aid

PD Dr. med. Hans Worthmann

Department of Neurology, Hannover Medical School

Dipl. Wirt.-Inf. Mareike Schulze

Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School

B12

Can the machine detect information we cannot? Developing an algorithm that can diagnose patients with functional tic-like movement disorder using machine learning.

Prof. Dr. Kirsten Müller-Vahl

Clinic of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School

Prof. Dr. Dr. Lars Schmidt-Thieme

Information Systems and Machine Learning Lab, University of Hildesheim

B13

Critical analysis of the scientific content of preprint servers

Prof. Dr. Roland Seifert

Institute of Pharmacology, Hannover Medical School

Prof. Dr. Tim Kacprowski

Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School

 

B14

Please contact digistrucmed@mh-hannover.de for information.

 

 

4. Jahrgang 2024/25

ID  

Projekttitel

Projektleitung

Kooperationspartner

P01 Computerized interpretation of fetal heart rate during labor including clinical parameters

PD Dr. Lars Brodowski
Gynecology and Obstetrics
Hannover Medical School

 

Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School
P02 Development, feasability and usability of a generic and secure application backed by a large language model with focus on patient education in patients with implantable defibrillators and heart failure Prof. Dr. David Duncker
Hannover Heart Rhythm Center
Department oft Cardiology and Angiology
Hannover Medical School
Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School
P03 Algorithm development using machine learning to distinguish between tics and functional tic-like movements in videos Prof. Dr. Kirsten Müller-Vahl
Clinic of Psychiatry, Social Psychiatry and Psychotherapy
Hannover Medical School
Institut für Informationsverarbeitung, Leibniz Universität Hannover

 Peter L. Reichertz Institute for Medical Informatics, TU Braunschweig and Hannover Medical School

P04 User-independent AI-based MRI analysis of hepatobiliary function in patients with primary sclerosing cholangitis (PSC) Prof. Dr. Kristina Ringe
Department of Diagnostic and Interventional Radiology
Hannover Medical School
Fraunhofer-Institute for Digital Medicine MEVIS
P05 Individualizing HCC surveillance based on an integrative systems medicine approach Prof. Dr. Markus Cornberg
Centre for Individualised Infection Medicine (CiiM), Hannover,
Dept. of Gastroenterology, Hepatology and Endocrinology
Hannover Medical School
Division Data Science in Biomedicine Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School
P06 Implementation of an AI-supported mental health app in psychocardiology Prof. Dr. Kai G. Kahl
Department of Psychiatry, Social Psychiatry and Psychotherapy
Hannover Medical School

Institut für Wirtschaftsinformatik
Leibniz Universität Hannover

P07 Identification of biomarkers in hepatocellular carcinoma patients by combining advanced imaging techniques with machine learning approaches PD Dr. Anna Saborowski
Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology
Hannover Medical School
Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School
P08 Digital Twin for predicting road traffic injuries Prof. Dr. Thomas M. Deserno
Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School
Klinik für Unfallchirurgie
Hannover Medical School
P09 Fibromyalgia Rheumatica and Digital Pain Drawing (FibRDraw) Prof. Dr. Georg Behrens
Department of Rheumatology and Immunology
Hannover Medical School

Institute for Information Engineering, Ostfalia University of Applied Sciences

Department of Psychosomatics and Psychotherapy
Hannover Medical School

P10 Evaluation of the clinical utility of wearable fitness tracking devices to predict liver related outcomes of patients with liver cirrhosis Prof. Dr. Benjamin Maasoumy
Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology
Hannover Medical School

Division Data Science in Biomedicine, Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School

Trauma Department, Orthogeriatric Unit, Hannover Medical School

3. Jahrgang 2023/24

ID  

Projekttitel

Projektleitung

Kooperationspartner

P01

Heartbeat Measurements on eScooters for Continuous Health Monitoring

Prof. Dr. rer. nat. Dipl.-Ing. Thomas M. Deserno
Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School

Hannover Heart Rhythm Center, Department of Cardiology and Angiology, Hannover Medical School

P02

ldentification of risk factors for postoperative acute kidney injury after non-cardiac surgery

PD Dr. med. Thomas Stüber
Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School

Department of Nephrology and Hypertension, Hannover Medical School

Peter l. Reichertz Institute for Medical lnformatics ofTU Braunschweig and MHH, Hannover Medical School

P03

Delineating immune escape mechanisms in acute myeloid leukemia through single-cell analyses

Prof. Dr. med. Michael Heuser
Clinic for Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School

Pediatric Hematology and Oncology, Hannover Medical School

Division Data Science in Biomedicine, Peter L. Reichertz Institute for Medical Informatics, TU Braunschweig and Hannover Medical School

P04

Ambulatory assessment of online shopping activities in patients with compulsive buying-shopping disorder

Prof. Dr. med. Dr. phil. Astrid Müller
Department of Psychosomatic Medicine and Psychotherapy
Hannover Medical School

Fakulty III - Media, Information and Design, Hochschule Hannover - University of Applied Sciences and Arts

P06

Development of a bioinformatical tool to predict clinical responses to CFTR modulator therapy by integrating microbial metagenomics, inflammatory cell transcriptomics and secretomics

Prof. Dr. med. Anna-Maria Dittrich
Pediatric Pneumology, Allergy and Neonatology, Hannover Medical School

Research Core Unit Genomics, Hannover Medical School

P07

Towards AI-based registration for advanced functional lung imaging

Prof. Dr. med. Jens Vogel-Claussen
Institute for Diagnostic and Interventional Radiology
Hannover Medical School

 

P08

Unsupervised identification of prognostic cell type signatures for CNS infiltration in ALL

Prof. Dr. med. Martin Stanulla
Pediatric Hematology and Oncology, Hannover Medical School

German Center for Lung Research Center, Hannover Medical School

P09

Inter-hospital Transfer for Endovascular Treatment in Acute Stroke Care using the Smart Application "VIZ"

PD Dr. med. Hans Worthmann
Department of Neurology,  Hannover Medical School

Peter L. Reichertz Institute for medical informatics of TU Braunschweig and MHH

P10

Characterization of Ambulatory Blood Pressure Monitoring (ABPM) Profiles Using Data Mining and Machine Learning in Healthy and Diseased Children

Prof. Dr. med. Anette Melk,  PhD
Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School
 

Prof. Dr.-Ing. Steffen Oeltze-Jafra

Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School

Center of Pediatric and Adolescent Medicine, University Hospital Heidelberg

P11

AI-based image analysis in pediatric echocardiography to improve the monitoring of relevant parameters in children with pulmonary hypertension

Dr.-Ing. Mohamed Yaseen Jabarulla
Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School

 

Dr. med. Theodor Uden

Pediatric Cardiology and Pediatric Intensive Care Medicine

-

P12

Is blended treatment with a WebApp-based therapy of mental disorders after life-threatening cardiac events more effective compared to non-blended treatment?

Prof. Dr. med. Kai G. Kahl
Department of Psychiatry, Social Psychiatry and Psychotherapy
Hannover Medical School

Fkt. IV, Abt. Informatik, Hochschule Hannover

2. Jahrgang 2022/23

Projekttitel

Projektleitung

Kooperationspartner

P01 - (Semi-) Automated procedures to find arguments for bioethical analyses

Prof. Dr. Sabine Salloch

Institute of Ethics, History and Philosophy of Medicine
Hannover Medical School

Institute for Information Systems
TU Braunschweig;

Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School

P02 - Tracking fake papers in scientific journals

Prof. Dr. Roland Seifert

Institute of Pharmacology, Hannover Medical School

Peter L. Reichertz Institute for Medical Informatics, TU Braunschweig and Hannover Medical School

P03 - Deciphering long-term consequences of HCV infection after viral elimination (Long-HepC) using Omics Integration

Prof. Dr. Markus Cornberg

Centre for Individualised Infection Medicine (CiiM);
Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School

Peter L. Reichertz Institute for Medical Informatics
of the TU Braunschweig and the Hannover Medical School
P04 - Entwicklung und Evaluation einer App zur Unterstützung von Patientinnen mit erblichen Brust- und Eierstockkrebs nach der genetischen Beratung

PD Dr.  Anke K. Bergmann

Department of Human Genetics,

Hannover Medical School

 

Prof. Dr.-Ing. Steffen Oeltze-Jafra

Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School

Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School

P05 - Predictive immune biomarkers in renal cancer: Compare immune landscape of tumors in native and transplanted (immunocompromised) kidneys

Prof. Dr. Jan Hinrich Bräsen

Institute of Pathology
Hannover Medical School

Technical University of Braunschweig;

Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School

P06 - Entwicklung von Prädiktionsmodellen für das postoperative Nierenversagen bei Kindern nach Herzoperationen unter Einsatz der Herzlungenmaschine

PD Dr. Martin Böhne

Pädiatrische Kardiologie und Intensivmedizin, Medizinische Hochschule Hannover

Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School
P07 - Development of Translational Scores for a Quantitative and Time-Dependent Assessment of Disease Severity in Patients

Prof. Dr. André Bleich

Laboratory Animal Science, Hannover Medical School

Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School
P08 - Clinical evaluation with a WebApp-based therapy of mental disorders after life-threatening cardiac
events

Prof. Dr. Kai G. Kahl

Department of Psychiatry, Social Psychiatry and Psychotherapy
Hannover Medical School

Department of Cardiology and Angiology
Hannover Medical School;

Abteilung für Informatik, Hochschule Hannover

P09 - Next generation Flow-Cytometry to quantify and characterize the leukemic stem cell population in acute myeloid leukemia

Dr. Dr, Adrian Schwarzer

Hematology, Hemostasis, Oncology and Stem Cell Transplantation
Institute of Experimental Hematology,
Hannover Medical School

Peter L. Reichertz Institute for Medical Informatics
of TU Braunschweig and Hannover Medical School;

Clinic of Pediatric Hematology, Hannover Medical School

P10 - Towards identifying genetic determinants of antibiotic resistance in clinical Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae isolates

Prof. Dr.  Susanne Häußler

Institute for Molecular Bacteriology, TWINCORE

Helmholtz Centre for Infection Research (HZI)

1. Jahrgang 2021/22

Projekttitel

Projektleitung

Kooperationspartner

P03 - Development of an AI-based algorithm to predict kidney injury in stem cell transplant patients

Dr. Gernot Beutel

Hämatologie, Hämostaseologie, Onkologie und Stammzell-transplantation

Medizinische Hochschule Hannover

Klinikum Braunschweig, Klinik für Nephrologie, Rheumatologie, Blutreinigungsverfahren, Prof. Dr. Jan T. Kielstein

P06 - Next generation Flow-Cytometry to detect minimal residual disease in acute myeloid leukemia

Dr. Dr. Adrian Schwarzer

Hämatologie, Hämostaseologie, Onkologie und Stammzell-transplantation

Medizinische Hochschule Hannover

Peter L. Reichertz Institut für Medizinische Informatik

P07 - The Inner Clock - Introduction and use of a smart communication tool to improve the emergency care of stroke patients

PD Dr. Hans Worthmann

Neurologie, Neuroradiologie

Medizinische Hochschule Hannover

Hochschule Hannover,

Peter L. Reichertz Institut für Medizinische Informatik

P08 - Determination of reference values of regional ventilation from CT scans of the lungs

Prof. Dr. Hoen-oh Shin

Diagnostische und Interventionelle Radiologie

Medizinische Hochschule Hannover

Fraunhofer MEVIS Institut für Digitale Medizin, Bremen

P09 - WebApp-based prevention and therapy of adjustment disorder after life-threatening cardiac events – the “AD-support” study

Prof. Dr. Kai G Kahl / Dr. Ivo-Aleksander Heitland

Psychiatrie, Sozialpsychiatrie und Psychotherapie

Medizinische Hochschule Hannover

Leibniz Universität Hannover, Information Systems and Management Institute (ISMI)

P10 - Reducing the socio-economic burden for rare disease patients using artificial intelligence (AI)

Prof. Dr. Annette Doris Wagner

Nieren- und Hochdruckerkrankungen

Medizinische Hochschule Hannover

Universitätsklinikum Marburg, Institut für Künstliche Intelligenz in der Medizin, Ada Health GmbH

 

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