Veröffentlichungen 2020

Ackermann M, Mentzer SJ, Kolb M, Jonigk D.

Inflammation and intussusceptive angiogenesis in COVID-19: everything in and out of flow.

Eur Respir J. 2020 Nov 12;56(5):2003147. doi: 10.1183/13993003.03147-2020. Print 2020 Nov.PMID: 33008942 Free PMC article.

Ackermann M, Stark H, Neubert L, Schubert S, Borchert P, Linz F, Wagner WL, Stiller W, Wielpütz M, Hoefer A, Haverich A, Mentzer SJ, Shah HR, Welte T, Kuehnel M, Jonigk D. 

Morphomolecular motifs of pulmonary neoangiogenesis in interstitial lung diseases.

Eur Respir J. 2020 Mar 12;55(3):1900933. doi: 10.1183/13993003.00933-2019. Print 2020 Mar.

Ackermann M, Verleden SE, Kuehnel M, Haverich A, Welte T, Laenger F, Vanstapel A, Werlein C, Stark H, Tzankov A, Li WW, Li VW, Mentzer SJ, Jonigk D. 

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.

N Engl J Med. 2020 Jul 9;383(2):120-128. doi: 10.1056/NEJMoa2015432. Epub 2020 May 21.

Ackermann M, Mentzer SJ, Jonigk D.

Pulmonary Vascular Pathology in Covid-19. Reply.

N Engl J Med. 2020 Aug 27;383(9):888-889. doi: 10.1056/NEJMc2022068. Epub 2020 Jul 17.

Ackermann M, Mentzer SJ, Jonigk D.

Visualization of SARS-CoV-2 in the Lung. Reply.

N Engl J Med. 2020 Dec 31;383(27):2689-2690. doi: 10.1056/NEJMc2030450.

Adam BA, Kikic Z, Wagner S, Bouatou Y, Gueguen J, Drieux F, Reid G, Du K, Bräsen JH, D'Agati VD, Drachenberg CB, Farkash EA, Farris AB, Geldenhuys L, Loupy A, Nickeleit V, Rabant M, Randhawa P, Regele H, Mengel M.

Intragraft Gene Expression in Native Kidney BK Virus Nephropathy versus T‐Cell Mediated Rejection: Prospects for Molecular Diagnosis and Risk Prediction.

Am J Transplant. 2020 Dec;20(12):3486-3501. doi: 10.1111/ajt.15980. Epub 2020 May 29.PMID: 32372431

Al Krinawe Y, Esmaeilzadeh M, Hartmann C, Krauss JK, Hermann EJ. 

Pediatric rosette-forming glioneuronal tumor of the septum pellucidum.

Childs Nerv Syst. 2020 Nov;36(11):2867-2870. doi: 10.1007/s00381-020-04575-w. Epub 2020 Mar 26.PMID: 32219524

Banan R, Stichel D, Bleck A, Hong B, Lehmann U, Suwala A, Reinhardt A, Schrimpf D, Buslei R, Stadelmann C, Ehlert K, Prinz M, Acker T, Schittenhelm J, Kaul D, Schweizer L, Capper D, Harter PN, Etminan N, Jones DTW, Pfister SM, Herold-Mende C, Wick W, Sahm F, von Deimling A, Hartmann C, Reuss DE.

Infratentorial IDH-mutant astrocytoma is a distinct subtype.

Acta Neuropathol. 2020 Oct;140(4):569-581. doi: 10.1007/s00401-020-02194-y. Epub 2020 Aug 10.PMID: 32776277

Bartels S, Hasemeier B, Vogtmann J, Schipper E, Büsche G, Schlue J, Kreipe H, Lehmann U.

Feasibility of Combined Detection of Gene Mutations and Fusion Transcripts in Bone Marrow Trephines from Leukemic Neoplasms.

J Mol Diagn. 2020 Apr;22(4):591-598. doi: 10.1016/j.jmoldx.2020.01.004. Epub 2020 Feb 7.PMID: 32036087

Bartels S, Faisal M, Büsche G, Schlue J, Hasemeier B, Schipper E, Vogtmann J, Westphal L, Lehmann U, Kreipe H.

Mutations associated with age-related clonal hematopoiesis in PMF patients with rapid progression to myelofibrosis.

Leukemia. 2020 May;34(5):1364-1372. doi: 10.1038/s41375-019-0668-5. Epub 2019 Nov 27.PMID: 31776465

Bartels S, Faisal M, Büsche G, Schlue J, Hasemeier B, Schipper E, Vogtmann J, Westphal L, Lehmann U, Kreipe H.

[Bone marrow fibrosis in primary myelofibrosis in relation to myelodysplasia- and age-related mutations of hematopoietic cells].

Pathologe. 2020 Dec;41(Suppl 2):124-128. doi: 10.1007/s00292-020-00828-2.PMID: 33113046 Review. German.

Behling F, Barrantes-Freer A, Behnes C L, Stockhammer F, Rohde V,  Adel-Horowski A, Rodríguez-Villagra OA, Barboza MA, Brück W, Lehmann U, Stadelmann C, Hartmann C. 

Expression of Olig2, Nestin, NogoA and AQP4 have no impact on overall survival in IDH-wildtype glioblastoma.

PLoS One. 2020 Mar 11;15(3):e0229274. doi: 10.1371/journal.pone.0229274. eCollection 2020.PMID: 32160197 Free PMC article.

Behr J, Günther A, Bonella F, Dinkel J, Fink L, Geiser T, Geißler K, Gläser S, Handzhhiev S, Jonigk D, Koschel D, Kreuter M, Leuschner G, Markart P, Prasse A, Schönfeld N, Schupp JC, Sitter H, Müller-Quernheim J, Costabel U. 

[German Guideline for Idiopathic Pulmonary Fibrosis].

Pneumologie. 2020 May;74(5):263-293. doi: 10.1055/a-1120-3531. Epub 2020 Mar 30.PMID: 32227328 German.

Bogaard HJ , Legchenko E , Ackermann M , Kühnel MP, Jonigk DD, Chaudhary KR, Sun X, Stewart DJ, Hansmann G. 

The Adult Sprague-Dawley Sugen-Hypoxia Rat Is Still "the One:" A Model of Group 1 Pulmonary Hypertension: Reply to Le Cras and Abman.

Am J Respir Crit Care Med. 2020 Mar 1;201(5):621-624. doi: 10.1164/rccm.201910-1983LE.PMID: 31769697 Free PMC article. No abstract available.

Bojkova D, Bechtel M, McLaughlin KM, McGreig JE, Klann K, Bellinghausen C, Rohde G, Jonigk D, Braubach P, Ciesek S, Münch C, Wass MN, Michaelis M, Cinatl J Jr.

Aprotinin Inhibits SARS-CoV-2 Replication.

Cells. 2020 Oct 30;9(11):2377. doi: 10.3390/cells9112377.PMID: 33143316 

Bork T, Liang W, Yamahara K, Lee P, Tian Z, Liu S, Schell C, Thedieck K, Hartleben B, Patel K, Tharaux PL, Lenoir O, Huber TB.

Podocytes maintain high basal levels of autophagy independent of mtor signaling.

Autophagy. 2020 Nov;16(11):1932-1948. doi: 10.1080/15548627.2019.1705007. Epub 2019 Dec 23.PMID: 31865844

Calabrese F, Schiavon M, Perissinotto E, Lunardi F, Marulli G, Di Gregorio G, Pezzuto F, Edith Vuljan S, Forin E, Wiegmann B, Jonigk D, Warnecke G, Rea F.

Organ Care System Lung resulted in lower apoptosis and iNOS expression in donor lungs.

Am J Transplant. 2020 Dec;20(12):3639-3648. doi: 10.1111/ajt.16187. Epub 2020 Sep 3.PMID: 32652873

Christgen M, Bartels S, van Luttikhuizen JL, Bublitz J, Rieger LU, Christgen H, Stark H, Sander B, Lehmann U, Steinemann D, Derksen PWB, Kreipe H.

E-cadherin to P-cadherin switching in lobular breast cancer with tubular elements.

Mod Pathol. 2020 Dec;33(12):2483-2498. doi: 10.1038/s41379-020-0591-3. Epub 2020 Jun 22.PMID: 32572153 Free PMC article.

Christgen M, Gluz O, Harbeck N, Kates RE, Raap M, Christgen H, Clemens M, Malter W, Nuding B, Aktas B, Kuemmel S, Reimer T, Stefek A, Krabisch P, Just M, Augustin D, Graeser M, Baehner F, Wuerstlein R, Nitz U, Kreipe H; West German Study Group PlanB Investigators.

Differential impact of prognostic parameters in hormone receptor-positive lobular breast cancer.

Cancer. 2020 Nov 15;126(22):4847-4858. doi: 10.1002/cncr.33104. Epub 2020 Aug 11.PMID: 32780421

Danov O, Wolff M, Bartel S, Böhlen S, Obernolte H, Wronski S, Jonigk D, Hammer B, Kovacevic D, Reuter S, Krauss-Etschmann S, Sewald K.

Cigarette Smoke Affects Dendritic Cell Populations, Epithelial Barrier Function, and the Immune Response to Viral Infection With H1N1.

Front Med (Lausanne). 2020 Nov 6;7:571003. doi: 10.3389/fmed.2020.571003. eCollection 2020.PMID: 33240904 Free PMC article.

Delgado SJ, Dehmel S, Twisterling E, Wichmann J, Jonigk D, Warnecke G, Braubach P, Fieguth HG, Wilkens L, Dahlmann F, Kaup FJ, Eggel A, Knauf S, Sewald K, Braun A.

Disruptive anti-IgE Inhibitors Prevent Mast Cell–Dependent Early Airway Response in Viable Atopic Lung Tissue.

J Allergy Clin Immunol. 2020 Feb;145(2):719-722.e1. doi: 10.1016/j.jaci.2019.11.002. Epub 2019 Dec 16.PMID: 31858993 No abstract available.

Derlin T, Werner RA, Lafos M, Henkenberens C, von Klot C AJ, Sommerlath Sohns J, Ross TL, Bengel FM. 

Neuroendocrine Differentiation and Response to PSMA-Targeted Radioligand Therapy in Advanced Metastatic Castration-Resistant Prostate Cancer: a Single-Center Retrospective Study.

J Nucl Med. 2020 Nov;61(11):1602-1606. doi: 10.2967/jnumed.120.241588. Epub 2020 Mar 13. PMID: 32169910.

Ditsch N, Untch M, Kolberg-Liedtke C, Jackisch C, Krug D, Friedrich M, Janni W, Müller V, Albert US, Banys-Paluchowski M, Bauerfeind I, Blohmer JU, Budach W, Dall P, Diel I, Fallenberg EM, Fasching PA, Fehm T, Gerber B, Gluz O, Hanf V, Harbeck N, Heil J, Huober J, Kreipe HH, Kühn T, Kümmel S, Loibl S, Lüftner D, Lux M, Maass N, Moebus V, Mundhenke C, Park-Simon TW, Reimer T, Rhiem K, Rody A, Schmidt M, Schneeweiss A, Solbach C, Solomayer EF, Stickeler E, Thomssen C, Witzel I, Wöckel A, Thill M.

AGO Recommendations for the Diagnosis and Treatment of Patients with Locally Advanced and Metastatic Breast Cancer: Update 2020.

Breast Care (Basel). 2020 Jun;15(3):294-309. doi: 10.1159/000508736. Epub 2020 Jun 10.PMID: 32774225 Free article. Review. No abstract available.

Donnert M, Elsheikh S, Arce-Rodriguez A, Pawar V, Braubach P, Jonigk D, Haverich A, Weiss S, Müsken M, Häussler S.

Targeting bioenergetics is key to counteracting the drug-tolerant state of biofilm-grown bacteria.

PLoS Pathog. 2020 Dec 22;16(12):e1009126. doi: 10.1371/journal.ppat.1009126. Online ahead of print.PMID: 33351859

Dowsett M, Ellis MJ, Dixon JM, Gluz O, Robertson J, Kates R, Suman VJ, Turnbull AK, Nitz U, Christgen M, Kreipe H, Kuemmel S, Bliss JM, Barry P, Johnston SR, Jacobs SA, Ma CX, Smith IE, Harbeck N.

Evidence-based guidelines for managing patients with primary ER+ HER2- breast cancer deferred from surgery due to the COVID-19 pandemic.

NPJ Breast Cancer. 2020 Jun 8;6:21. doi: 10.1038/s41523-020-0168-9. eCollection 2020.PMID: 32550266 Free PMC article.

Dywicki J, Buitrago-Molina LE, Pietrek J, Lieber M, Broering R, Khera T, Schlue J, Manns MP, Wedemeyer H, Jaeckel E, Hardtke-Wolenski M. 

Autoimmune hepatitis induction can occur in the liver.

Liver Int. 2020 Feb;40(2):377-381. doi: 10.1111/liv.14296. Epub 2019 Dec 1.PMID: 31724273

Eckermann M, Frohn J, Reichardt M, Osterhoff M, Sprung M, Westermeier F, Tzankov A, Werlein C, Kühnel M, Jonigk D, Salditt T.

3D virtual pathohistology of lung tissue from Covid-19 patients based on phase contrast X-ray tomography.

Elife. 2020 Aug 20;9:e60408. doi: 10.7554/eLife.60408.PMID: 32815517 Free PMC article.

Ernst P, Engmann B, Frietsch JJ, Schnetzke U, Scholl S, Theis B, Kreipe HH, Ernst T, Glaser A, Haferlach T, Koch T, Hochhaus A, Hilgendorf I.

A 19-year-old patient with atypical chronic myeloid leukemia.

Ann Hematol. 2020 May;99(5):1145-1148. doi: 10.1007/s00277-020-03992-w. Epub 2020 Mar 19.PMID: 32193626 Free PMC article. No abstract available.

Feist H, Hussein K, Blöcker T, Wohlschlaeger J. 

Pathoanatomical Lesions in Placentas With Excessively Hypercoiled Umbilical Cords: Frequent Detection of Massive Perivillous Fibrin Deposition.

Pediatr Dev Pathol. 2020 Mar-Apr;23(2):107-114. doi: 10.1177/1093526619865426. Epub 2019 Jul 25.PMID: 31345137

Feist H, Hussein K, Stucki-Koch A, Wohlschlaeger J, Hager T, Blöcker T, Heim A. 

Villitis of unknown etiology and chronic deciduitis are not associated with human papilloma virus and enterovirus infection.

Virchows Arch. 2020 Jul;477(1):73-81. doi: 10.1007/s00428-020-02765-0. Epub 2020 Feb 5. PMID: 32025822.

Fleißner F, Tudorache I, Christgen M, Cebotari S.

Cardiac Phlegmon: Infectious Endocarditis Causing Ventricular Wall Rupture.

Thorac Cardiovasc Surg Rep. 2020 Jan;9(1):e51-e54. doi: 10.1055/s-0040-1716391. Epub 2020 Nov 2.PMID: 33154880 Free PMC article.

Gambichler T, Doerler M, Nöpel-Dünnebacke S, Matschke J, Bräsen JH, Linke RP, Susok L. 

Haemorrhagic bullous lesions in cutaneous light-chain amyloidosis with smouldering myeloma.

J Eur Acad Dermatol Venereol. 2020 Jan;34(1):e13-e15. doi: 10.1111/jdv.15844. Epub 2019 Aug 30.PMID: 31390676 No abstract available.

Gleitz HFE, Dugourd AJF, Leimkühler NB, Snoeren IAM, Fuchs SNR, Menzel S, Ziegler S, Kröger N, Triviai I, Büsche G, Kreipe H, Banjanin B, Pritchard JE, Hoogenboezem R, Bindels EM, Schumacher N, Rose-John S, Elf S, Saez-Rodriguez J, Kramann R, Schneider RK.

Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN.

Blood. 2020 Oct 29;136(18):2051-2064. doi: 10.1182/blood.2019004095.PMID: 32726410 Free PMC article.

Gluz O, Kolberg-Liedtke C, Prat A, Christgen M, Gebauer D, Kates R, Paré L, Grischke EM, Forstbauer H, Braun M, Warm M, Hackmann J, Uleer C, Aktas B, Schumacher C, Kuemmel S, Wuerstlein R, Pelz E, Nitz U, Kreipe HH, Harbeck N.

Efficacy of deescalated chemotherapy according to PAM50 subtypes, immune and proliferation genes in triple-negative early breast cancer: Primary translational analysis of the WSG-ADAPT-TN trial.

Int J Cancer. 2020 Jan 1;146(1):262-271. doi: 10.1002/ijc.32488. Epub 2019 Jun 19.PMID: 31162838 Free article. Clinical Trial.

Greer M, Werlein C, Jonigk D. 

Surveillance for acute cellular rejection after lung transplantation.

Ann Transl Med. 2020 Mar;8(6):410. doi: 10.21037/atm.2020.02.127.PMID: 32355854 Free PMC article. Review.

Greimelmaier K, Wohlschläger J, Probst A, Hager T, Wardelmann E, Werlein C, Jonigk D, Müller KM.

[Mesothelial proliferation of the tunica vaginalis testis].

Pathologe. 2020 Jul;41(4):406-410. doi: 10.1007/s00292-020-00797-6.

Greite R, Derlin K, Hensen B, Thorenz A, Rong S, Chen R, Hellms S, Jang MS, Bräsen JH, Meier M, Willenberg I, Immenschuh S, Haller H, Luft FC, Panigrahy D, Hwang SH, Hammock BD, Schebb NH, Gueler F.

Early antihypertensive treatment and ischemia-induced acute kidney injury.

Am J Physiol Renal Physiol. 2020 Oct 1;319(4):F563-F570. doi: 10.1152/ajprenal.00078.2020. Epub 2020 Aug 17.PMID: 32799675

Greunz EM, Lemberger K, Catinaud J, Chenet B, Linke RP, Bräsen JH, Schmitz J, Bertelsen MF. 

Amyloidosis in Caracals (Caracal Caracal).

J Zoo Wildl Med. 2020 Mar 17;51(1):202-209. doi: 10.1638/2019-0005.PMID: 32212564

Griguolo G, Brasó-Maristany F, González-Farré B, Pascual T, Chic N, Saurí T, Kates R, Gluz O, Martínez D, Paré L, Tsvetkova V, Pesantez D, Vidal M, Adamo B, Muñoz M, Galván P, Barberá L, Cuatrecasas M, Christgen M, Kreipe H, Monge-Escartín I, Villagrasa P, Soy D, Giarratano T, Dieci MV, Conte P, Harbeck N, Guarneri V, Prat A.

ERBB2 mRNA Expression and Response to Ado-Trastuzumab Emtansine (T-DM1) in HER2-Positive Breast Cancer.

Cancers (Basel). 2020 Jul 14;12(7):1902. doi: 10.3390/cancers12071902.PMID: 32674482 Free PMC article.

Haake K, Neehus A-L , Buchegger T, Kühnel MP, Blank P, Philipp F, Oleaga-Quintas C, Schulz A, Grimley M, Goethe R, Jonigk D, Kalinke U, Boisson-Dupuis S, Casanova J-L , Bustamante J, Lachmann N. 

Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway.

Cells. 2020 Feb 19;9(2):483. doi: 10.3390/cells9020483.PMID: 32093117 Free PMC article.

Hack T, Bertram S, Blair H, Börger V, Büsche G, Denson L, Fruth E, Giebel B, Heidenreich O, Klein-Hitpass L, Kollipara L, Sendker S, Sickmann A, Walter C, von Neuhoff N, Hanenberg H, Reinhardt D, Schneider M, Rasche M.

Exposure of Patient-Derived Mesenchymal Stromal Cells to TGFB1 Supports Fibrosis Induction in a Pediatric Acute Megakaryoblastic Leukemia Model.

Mol Cancer Res. 2020 Oct;18(10):1603-1612. doi: 10.1158/1541-7786.MCR-20-0091. Epub 2020 Jul 8.PMID: 32641517

Höfer A, Jonigk D, Hartleben B, Verboom M, Hallensleben M, Hübscher SG, Manns MP, Jaeckel E, Taubert R.

DSA are associated with more graft injury, more fibrosis, and upregulation of rejection-associated transcripts in subclinical rejection.

Transplantation. 2020 Mar;104(3):551-561. doi: 10.1097/TP.0000000000003034.PMID: 31651790

Höfer A, Jonigk D, Hartleben B, Verboom M, Hallensleben M, Manns MP, Jaeckel E, Taubert R.

Non-invasive screening for subclinical liver graft injury in adults via donor-specific anti-HLA antibodies.

Sci Rep. 2020 Aug 28;10(1):14242. doi: 10.1038/s41598-020-70938-7.PMID: 32859929 Free PMC article.

Jöhrens K, von Wasielewski R, Kreipe HH, Forberger A, Jurmeister P, Dietel M, Stenzinger A, Fischer J.

[Quality assurance in diagnostic in situ hybridization-experience of QuIP].

Pathologe. 2020 Nov;41(6):614-620. doi: 10.1007/s00292-020-00832-6.PMID: 32945916 Review. German.

Jonigk D, Märkl B, Helms J.

COVID-19: what the clinician should know about post-mortem findings.

Intensive Care Med. 2021 Jan;47(1):86-89. doi: 10.1007/s00134-020-06302-0. Epub 2020 Nov 3.PMID: 33141245 Free PMC article. No abstract available.

Kanzelmeyer NK, Lerch C, Ahlenstiel-Grunow T, Bräsen JH, Haffner D, Pape L.

The role of protocol biopsies after pediatric kidney transplantation.

Medicine (Baltimore). 2020 Jun 5;99(23):e20522. doi: 10.1097/MD.0000000000020522.PMID: 32502003 Free PMC article.

Kamp JC, Jonigk DD, Hinrichs JB, Hoeper MM, Schönhofer B, Ernst D, Welte T, Suhling H.

Recurrent Life-threatening Pneumonitis in a 37-Year-Old Woman.

Chest. 2020 Sep;158(3):e127-e132. doi: 10.1016/j.chest.2020.03.066.PMID: 32892889

Kim EL , Sorokin M, Kantelhardt SR, Kalasauskas D, Sprang B, Fauss J, Ringel F, Garazha A, Albert E, Gaifullin N, Hartmann C, Naumann N, Bikar SE, Giese A, Buzdin A. 

Intratumoral heterogeneity and longitudinal changes in gene expression predict differential drug sensitivity in newly diagnosed and recurrent glioblastoma.

Cancers (Basel). 2020 Feb 24;12(2):520. doi: 10.3390/cancers12020520.PMID: 32102350 Free PMC article.

Kirchner M, Glade J, Lehmann U, Merkelbach-Bruse S, Hummel M, Lehmann A, Trautmann M, Kumbrink J, Jung A, Dietmaier W, Endris V, Kazdal D, Ploeger C, Evert M, Horst D, Kreipe H, Kirchner T, Wardelmann E, Büttner R, Weichert W, Dietel M, Schirmacher P, Stenzinger A, Pfarr N. 

NTRK testing: First results of the QuiP-EQA scheme and a comprehensive map of NTRK fusion variants and their diagnostic coverage by targeted RNA-based NGS assays.

Genes Chromosomes Cancer. 2020 Aug;59(8):445-453. doi: 10.1002/gcc.22853. Epub 2020 May 9. PMID: 32319699.

Kolberg-Liedtke C, Gluz O, Heinisch F, Feuerhake F, Kreipe H, Clemens M, Nuding B, Malter W, Reimer T, Wuerstlein R, Graeser M, Shak S, Nitz U, Kates R, Christgen M, Harbeck N.

Association of TILs with clinical parameters, Recurrence Score® results, and prognosis in patients with early HER2-negative breast cancer (BC)-a translational analysis of the prospective WSG PlanB trial.

Breast Cancer Res. 2020 May 14;22(1):47. doi: 10.1186/s13058-020-01283-w.PMID: 32408905 Free PMC article.

Kommoss FKF, Schwab C, Tavernar L, Schreck J, Wagner WL, Merle U, Jonigk D, Schirmacher P, Longerich T.

The Pathology of Severe COVID-19-Related Lung Damage.

Dtsch Arztebl Int. 2020 Jul 20;117(29-30):500-506. doi: 10.3238/arztebl.2020.0500.PMID: 32865490 Free PMC article.

Kreimann K, Jang MS, Rong S, Greite R, von Vietinghoff S, Schmitt R, Bräsen JH, Schiffer L, Gerstenberg J, Vijayan V, Dittrich-Breiholz O, Wang L, Karsten CM, Gwinner W, Haller H, Immenschuh S, Gueler F.

Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation.

Front Immunol. 2020 Aug 6;11:1204. doi: 10.3389/fimmu.2020.01204. eCollection 2020.PMID: 32849490 Free PMC article.

Lehner GM, Schacht V, Angela Y, Satzger I, Gutzmer R.

Erfolgreiche Behandlung eines metastasierenden Melanoms mit Talimogen laherparepvec (T-VEC) bei einer lebertransplantierten Patientin.

J Dtsch Dermatol Ges. 2020 Dec;18(12):1495-1497. doi: 10.1111/ddg.14284_g.PMID: 33373132 German. No abstract available.

Mayer U, Schmitz J, Bräsen JH, Pape L. 

Crescentic glomerulonephritis in children.

Pediatr Nephrol. 2020 May;35(5):829-842. doi: 10.1007/s00467-019-04436-y. Epub 2020 Feb 12.PMID: 32052153 Free PMC article.

Melchert J, Henningfeld KA, Richts S, Lingner T, Jonigk D, Pieler T. 

The secreted BMP antagonist ERFE is required for the development of a functional circulatory system in Xenopus.

Dev Biol. 2020 Mar 15;459(2):138-148. doi: 10.1016/j.ydbio.2019.12.007. Epub 2019 Dec 14.PMID: 31846624

Mishra A, Emamgholi F, Erlangga Z, Hartleben B, Unger K, Wolff K, Teichmann U, Kessel M, Woller N, Kühnel F, Dow LE, Manns MP, Vogel A, Lowe SW, Saborowski A, Saborowski M. 

Generation of focal mutations and large genomic deletions in the pancreas using inducible in vivo genome editing.

Carcinogenesis. 2020 May 14;41(3):334-344. doi: 10.1093/carcin/bgz108.PMID: 31170286

Mund E, Salem J, Kreipe HH, Hussein K.

Clinically latent and autopsy-verified inflammatory disorders and malignant tumours in transplant patients.

JJ Clin Pathol. 2020 Dec 28:jclinpath-2020-207080. doi: 10.1136/jclinpath-2020-207080. Epub ahead of print. PMID: 33372107.

Mynarek M, von Hoff K, Pietsch T, Ottensmeier H, Warmuth-Metz M, Bison B, Pfister S, Korshunov A, Sharma T, Jaeger N, Ryzhova M, Zheludkova O, Golanov A, Rushing EJ, Hasselblatt M, Koch A, Schüller U, von Deimling A, Sahm F, Sill M, Riemenschneider MJ, Dohmen H, Monoranu CM, Sommer C, Staszewski O, Mawrin C, Schittenhelm J, Brück W, Filipski K, Hartmann C, Meinhardt M, Pietschmann K, Haberler C, Slavc I, Gerber NU, Grotzer M, Benesch M, Schlegel PG, Deinlein F, von Bueren AO, Friedrich C, Juhnke BO, Obrecht D, Fleischhack G, Kwiecien R, Faldum A, Kortmann RD, Kool M, Rutkowski S. 

Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort.

J Clin Oncol. 2020 Jun 20;38(18):2028-2040. doi: 10.1200/JCO.19.03057. Epub 2020 Apr 24. PMID: 32330099.

Neubert L, Borchert P, Stark H, Hoefer A, Vogel-Claussen J, Warnecke G, Eubel H, Kuenzler P, Kreipe HH, Hoeper MM, Kuehnel M, Jonigk D. 

Molecular Profiling of Vascular Remodeling in Chronic Pulmonary Disease.

Am J Pathol. 2020 Jul;190(7):1382-1396. doi: 10.1016/j.ajpath.2020.03.008. Epub 2020 Apr 7. PMID: 32275906.

Niehues T, Özgür TT, Bickes M, Waldmann R, Schöning J, Bräsen J, Hagel C, Ballmaier M, Klusmann JH, Niedermayer A, Pannicke U, Enders A, Dückers G, Siepermann K, Hempel J, Schwarz K, Viemann D.

Mutations of the gene FNIP1 associated with a syndromic autosomal recessive immunodeficiency with cardiomyopathy and pre-excitation syndrome.

Eur J Immunol. 2020 Jul;50(7):1078-1080. doi: 10.1002/eji.201948504. Epub 2020 Apr 20. PMID: 32181500.

Nitz U, Gluz O, Kreipe HH, Christgen M, Kuemmel S, Baehner FL, Shak S, Aktas B, Braun M, Lüdtke-Heckenkamp K, Forstbauer H, Grischke EM, Nuding B, Darsow M, Schumacher C, Krauss K, Malter W, Thill M, Warm M, Wuerstlein R, Kates RE, Harbeck N.

The run-in phase of the prospective WSG-ADAPT HR+/HER2- trial demonstrates the feasibility of a study design combining static and dynamic biomarker assessments for individualized therapy in early breast cancer.

Ther Adv Med Oncol. 2020 Nov 23;12:1758835920973130. doi: 10.1177/1758835920973130. eCollection 2020.PMID: 33281950 Free PMC article.

Pfarr N, Kirchner M, Lehmann U, Leichsenring J, Merkelbach-Bruse S, Glade J, Hummel M, Stögbauer F, Lehmann A, Trautmann M, Kumbrink J, Jung A, Dietmaier W, Endris V, Kazdal D, Evert M, Horst D, Kreipe H, Kirchner T, Wardelmann E, Lassen U, Büttner R, Weichert W, Dietel M, Schirmacher P, Stenzinger A. 

Testing NTRK testing: Wet-lab and in silico comparison of RNA-based targeted sequencing assays.

Genes Chromosomes Cancer. 2020 Mar;59(3):178-188. doi: 10.1002/gcc.22819. Epub 2019 Nov 18.PMID: 31652375

Reifenrath J, Janßen HC, Warwas DP, Kietzmann M, Behrens P, Willbold E, Fedchenko M, Angrisani N.

Implant-based direction of magnetic nanoporous silica nanoparticles - influence of macrophage depletion and infection.

Nanomedicine. 2020 Nov;30:102289. doi: 10.1016/j.nano.2020.102289. Epub 2020 Aug 26.PMID: 32861030

Saborowski A, Lehmann U, Vogel A.

FGFR inhibitors in cholangiocarcinoma: what's now and what's next?

Ther Adv Med Oncol. 2020 Sep 16;12:1758835920953293. doi: 10.1177/1758835920953293. PMID: 32983265; PMCID: PMC7498964.  Review.

Schaadt NS, Schönmeyer R, Forestier G, Brieu N, Braubach P, Nekolla K, Meyer-Hermann M, Feuerhake F. 

Graph-based description of tertiary lymphoid organs at single-cell level.

PLoS Comput Biol. 2020 Feb 21;16(2):e1007385. doi: 10.1371/journal.pcbi.1007385. eCollection 2020 Feb.PMID: 32084130 Free PMC article.

Schirmer B, Rother T, Bruesch I, Bleich A, Werlein C, Jonigk D, Seifert R, Neumann D. 

Genetic deficiency of the histamine H4-receptor reduces experimental colorectal carcinogenesis in mice.

Cancers (Basel). 2020 Apr 8;12(4):912. doi: 10.3390/cancers12040912.PMID: 32276475 Free PMC article.

Schaumann N, Hussein K.

Hepatic and Adrenocortical Choristomas in the Placenta.

Fetal Pediatr Pathol. 2020 Jul 22:1-10. doi: 10.1080/15513815.2020.1792594. Online ahead of print.PMID: 32696693

Schimmel K, Jung M, Foinquinos A, José GS, Beaumont J, Bock K, Grote-Levi L, Xiao K, Bär C, Pfanne A, Just A, Zimmer K, Ngoy S, López B, Ravassa S, Samolovac S, Janssen-Peters H, Remke J, Scherf K, Dangwal S, Piccoli MT, Kleemiss F, Kreutzer FP, Kenneweg F, Leonardy J, Hobuß L, Santer L, Do QT, Geffers R, Braesen JH, Schmitz J, Brandenberger C, Müller DN, Wilck N, Kaever V, Bähre H, Batkai S, Fiedler J, Alexander KM, Wertheim BM, Fisch S, Liao R, Diez J, González A, Thum T.

Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction.

Circulation. 2020 Mar 3;141(9):751-767. doi: 10.1161/CIRCULATIONAHA.119.042559. Epub 2020 Jan 17.PMID: 31948273 Free PMC article.

Schirmer B, Rother T, Bruesch I, Bleich A, Werlein C, Jonigk D, Seifert R, Neumann D.

Genetic Deficiency of the Histamine H4-Receptor Reduces Experimental Colorectal Carcinogenesis in Mice.

Cancers (Basel). 2020 Apr 8;12(4):912. doi: 10.3390/cancers12040912.PMID: 32276475 Free PMC article.

Schünemann C, Göhring G, Behrens YL, Kreipe HH, Ganser A, Thol F.

Histiocytic sarcoma progressing from follicular lymphoma and mimicking acquired hemophagocytic lymphohistiocytosis.

Ann Hematol. 2020 Oct;99(10):2441-2443. doi: 10.1007/s00277-020-04190-4. Epub 2020 Aug 17.PMID: 32808104 Free PMC article. No abstract available.

Schweizer L, Thierfelder F, Thomas C, Soschinski P, Suwala A, Stichel D, Wefers AK, Wessels L, Misch M, Kim HY, Jödicke R, Teichmann D, Kaul D, Kahn J, Bockmayr M, Hasselblatt M, Younsi A, Unterberg A, Knie B, Walter J, Al Safatli D, May SA, Jödicke A, Ntoulias G, Moskopp D, Vajkoczy P, Heppner FL, Capper D, Hartmann W, Hartmann C, von Deimling A, Reuss DE, Schöler A, Koch A.

Molecular characterization of CNS paragangliomas identifies cauda equina paragangliomas as a distinct tumor entity.

Acta Neuropathol. 2020 Dec;140(6):893-906. doi: 10.1007/s00401-020-02218-7. Epub 2020 Sep 14.PMID: 32926213 Free PMC article.

Sen P, Helmke A, Liao CM, Sörensen-Zender I, Rong S, Bräsen JH, Melk A, Haller H, von Vietinghoff S, Schmitt R. 

SerpinB2 Regulates Immune Response in Kidney Injury and Aging.

J Am Soc Nephrol. 2020 May;31(5):983-995. doi: 10.1681/ASN.2019101085. Epub 2020 Mar 24.PMID: 32209589

Serth J, Peters I, Dubrowinskaja N, Reese C, Albrecht K, Klintschar M, Lafos M, Grote A, Becker A, Hennenlotter J, Stenzl A, Tezval H, Kuczyk MA. 

Age-, tumor-, and metastatic tissue-associated DNA hypermethylation of a T-box brain 1 locus in human kidney tissue.

Clin Epigenetics. 2020 Feb 18;12(1):33. doi: 10.1186/s13148-020-0823-x.PMID: 32070431 Free PMC article.

Sieweke J-T, Akin M, Stetskamp S, Riehle C, Jonigk D, Flierl U, Pfeffer TJ, Hirsch V, Dutzmann J, Hoeper MM, Kühn C, Bauersachs J, Schäfer A. 

Mechanical Circulatory Support in Refractory Cardiogenic Shock due to Influenza Virus-Related Myocarditis.

Eur Respir J. 2020 Sep 3;56(3):2000925. doi: 10.1183/13993003.00925-2020. PMID: 32398305; PMCID: PMC7469974.

Slabik C, Kalbarczyk M, Danisch S, Zeidler R, Klawonn F, Volk V, Krönke N, Feuerhake F, Ferreira de Figueiredo C, Blasczyk R, Olbrich H, Theobald SJ, Schneider A, Ganser A, von Kaisenberg C, Lienenklaus S, Bleich A, Hammerschmidt W, Stripecke R.

CAR-T Cells Targeting Epstein-Barr Virus gp350 Validated in a Humanized Mouse Model of EBV Infection and Lymphoproliferative Disease.

Mol Ther Oncolytics. 2020 Aug 8;18:504-524. doi: 10.1016/j.omto.2020.08.005. eCollection 2020 Sep 25.PMID: 32953984 Free PMC article.

Soudah B.

Metastasen in der Leber.

CYTO-INFO. 2020; 3: 79-85

Soudah B, Oberndörfer AK.

Zytologie der Speicheldrüsen mit Differentialdignosen.

CYTO-INFO. 2020; 1: 125-131

Stahl K, Bräsen JH, Hoeper MM, David S.

Direct evidence of SARS-CoV-2 in gut endothelium.

Intensive Care Med. 2020 Nov;46(11):2081-2082. doi: 10.1007/s00134-020-06237-6. Epub 2020 Sep 11.PMID: 32915253 Free PMC article. No abstract available.

Stauss RD, Grosse GM, Neubert L, Falk CS, Jonigk D, Kühnel MP, Gabriel MM, Schuppner R, Lichtinghagen R, Wilhelmi M, Weissenborn K, Schrimpf C.

Distinct systemic cytokine networks in symptomatic and asymptomatic carotid stenosis.

Sci Rep. 2020 Dec 15;10(1):21963. doi: 10.1038/s41598-020-78941-8.PMID: 33319833 Free PMC article.

Struck AK, Klotz D, Hülskötter K, Wohlsein P, Schmitz J, Bräsen JH, Distl O.

Complex segregation analysis of familial amyloidosis in Oriental shorthair cats.

Vet J. 2020 Nov;265:105552. doi: 10.1016/j.tvjl.2020.105552. Epub 2020 Oct 1.PMID: 33129552

Szepes M, Melchert A, Dahlmann J, Hegermann J, Werlein C, Jonigk D, Haverich A, Martin U, Olmer R, Gruh I.

Dual Function of iPSC-Derived Pericyte-Like Cells in Vascularization and Fibrosis-Related Cardiac Tissue Remodeling In Vitro.

Int J Mol Sci. 2020 Nov 25;21(23):8947. doi: 10.3390/ijms21238947.PMID: 33255686 Free PMC article.

Thiele T, Seeliger T, Witte T, Sander B, Skripuletz T, Ernst D.

[Severe polyneuropathy in primary Sjögren's syndrome : Sjögren's syndrome should be considered in patients with motor neuropathy].

Z Rheumatol. 2020 Sep;79(7):707-709. doi: 10.1007/s00393-020-00821-3.PMID: 32474638 German.

Tumpara S, Martinez-Delgado B, Gomez-Mariano G, Liu B, DeLuca DS, Korenbaum E, Jonigk D, Jugert F, Wurm FM, Wurm MJ, Welte T, Janciauskiene S.

The Delivery of α1-Antitrypsin Therapy Through Transepidermal Route: Worthwhile to Explore.

Front Pharmacol. 2020 Jul 3;11:983. doi: 10.3389/fphar.2020.00983. eCollection 2020.PMID: 32719598 Free PMC article.

Tzankov A, Jonigk D.

Unlocking the lockdown of science and demystifying COVID-19: how autopsies contribute to our understanding of a deadly pandemic.

Virchows Arch. 2020 Sep;477(3):331-333. doi: 10.1007/s00428-020-02887-5. Epub 2020 Jul 9.PMID: 32648040 Free PMC article. No abstract available.

Van Alem CMA, Schmidbauer M, Rong S, Derlin K, Schmitz J, Bräsen JH, Thorenz A, Chen R, Ruben JM, Winter EM, Schilperoort M, Kooijman S, Lalai RA, Metselaar JM, Klemann C, Meier M, van Kooten C, Gueler F, Rotmans JI. 

Liposomal delivery improves the efficacy of prednisolone to attenuate renal inflammation in a mouse model of acute renal allograft rejection.

Transplantation. 2020 Apr;104(4):744-753. doi: 10.1097/TP.0000000000003060.PMID: 31929419 Free PMC article.

Verleden SE, Vanstapel A, De Sadeleer L, Weynand B, Boone M, Verbeken E, Piloni D, Van Raemdonck D, Ackermann M, Jonigk DD, Verschakelen J, Wuyts WA. 

Quantitative analysis of airway obstruction in lymphangio-leio-myomatosis.

Eur Respir J. 2020 Jul 2;56(1):1901965. doi: 10.1183/13993003.01965-2019. PMID: 32108050; PMCID: PMC7330132.

Verleden SE, Von der Thüsen J, Roux A, Brouwers ES, Braubach P, Kuehnel M, Laenger F, Jonigk D. 

When tissue is the issue: A histological review of chronic lung allograft dysfunction.

Am J Transplant. 2020 Oct;20(10):2644-2651. doi: 10.1111/ajt.15864. Epub 2020 Apr 15. PMID: 32185874.

Viereck J, Bührke A, Foinquinos A, Chatterjee S, Kleeberger JA, Xiao K, Janssen-Peters H, Batkai S, Ramanujam D, Kraft T, Cebotari S, Gueler F, Beyer AM, Schmitz J, Bräsen JH, Schmitto JD, Gyöngyösi M, Löser A, Hirt MN, Eschenhagen T, Engelhardt S, Bär C, Thum T.

Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophy.

Eur Heart J. 2020 Sep 21;41(36):3462-3474. doi: 10.1093/eurheartj/ehaa519.PMID: 32657324

Volkmann J, Schmitz J, Nordlohne J, Dong L, Helmke A, Sen P, Immenschuh S, Bernhardt WM, Gwinner W, Bräsen JH, Schmitt R, Haller H, von Vietinghoff S. 

Kidney injury enhances renal G-CSF expression and modulates granulopoiesis and human neutrophil CD177 in vivo..

Clin Exp Immunol. 2020 Jan;199(1):97-108. doi: 10.1111/cei.13372. Epub 2019 Sep 30.PMID: 31509227 Free PMC article.

von Stillfried S, Bülow RD, Röhrig R, Knüchel-Clarke R, Boor P; DeRegCOVID.

Autopsy registry can facilitate COVID-19 research.

EMBO Mol Med. 2020 Aug 7;12(8):e12885. doi: 10.15252/emmm.202012885. Epub 2020 Jul 3.PMID: 32559338 Free PMC article.

Werlein C, Seidel A, Warnecke G, Gottlieb J, Laenger F, Jonigk D. 

Lung Transplant Pathology: An Overview on Current Entities and Procedures.

Surg Pathol Clin. 2020 Mar;13(1):119-140. doi: 10.1016/j.path.2019.11.003.PMID: 32005428 Review.

Willers M, Ulas T, Völlger L, Vogl T, Heinemann AS, Pirr S, Pagel J, Fehlhaber B, Halle O, Schöning J, Schreek S, Löber U, Essex M, Hombach P, Graspeuntner S, Basic M, Bleich A, Cloppenborg-Schmidt K, Künzel S, Jonigk D, Rupp J, Hansen G, Förster R, Baines JF, Härtel C, Schultze JL, Forslund SK, Roth J, Viemann D.

S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants.

Gastroenterology. 2020 Dec;159(6):2130-2145.e5. doi: 10.1053/j.gastro.2020.08.019. Epub 2020 Aug 15.PMID: 32805279 Free article.

Yuzefovych Y, Valdivia E, Rong S, Hack F, Rother T, Schmitz J, Bräsen JH, Wedekind D, Moers C, Wenzel N, Gueler F, Blasczyk R, Figueiredo C.

Genetic Engineering of the Kidney to Permanently Silence MHC Transcripts During ex vivo Organ Perfusion.

Front Immunol. 2020 Feb 19;11:265. doi: 10.3389/fimmu.2020.00265. eCollection 2020.

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