Adenoviruses and Immune Evasion

Aichane, K., and Windheim, M. (2023) Catch me if you can – wie Adenoviren das humane Immunsystem austricksen. BIOspektrum 06.23: 578-580 (in German)

Pokoyski, C., Baars, W., Windheim, M., Reubold, T.F., Zischke, J., Brinkmann, A., Kay-Fedorov, P.C., Schwinzer, R. (2023) Expression of viral CD45 ligand E3/49K on porcine cells reduces human anti-pig immune responses. Scientific Reports 13: 17218

Windheim, M., Reubold, T.F., Aichane, K., Gaestel, M., and Burgert, H.G. (2023) Enforced dimerization of CD45 by the adenovirus E3/49K protein inhibits T cell receptor signaling. Journal of Virology 97: e0189822.

Windheim, M., Honing, S., Leppard, K.N., Butler, L., Seed, C., Ponnambalam, S., and Burgert, H.G. (2016) Sorting motifs in the cytoplasmic tail of the immunomodulatory E3/49K protein of species D adenoviruses modulate cell Surface expression and ectodomain shedding. Journal of Biological Chemistry 291, 6796-6812.

Windheim, M., Southcombe, J.H., Kremmer, E., Chaplin, L., Urlaub, D., Falk, C.S., Claus, M., Mihm, J., Braithwaite, M., Dennehy, K., Renz, H., Sester, M., Watzl, C., and Burgert, H.G. (2013) A unique secreted adenovirus E3 protein binds to the leukocyte common antigen CD45 and modulates leukocyte functions. Proceedings of the National Academy of Sciences of the United States of America 110, E4884-4893.

Windheim, M., Hilgendorf, A., Burgert, H.-G. (2004) Immune evasion by adenovirus E3 proteins: Exploitation of intracellular trafficking pathways. Current Topics in Microbiology and Immunology 273: 29-85.

Windheim, M., Burgert, H.-G. (2002) Characterization of E3/49K, a novel, highly glycosylated E3 protein of the epidemic keratoconjunctivitis-causing adenovirus type 19a. Journal of Virology 76: 755-66.

Burgert, H.-G., Ruzsics, Z., Obermeier, S., Hilgendorf, A., Windheim, M., Elsing, A. (2002) Subversion of host defense mechanisms by adenoviruses. Current Topics in Microbiology and Immunology 269: 273-318.

Blusch, J.H., Deryckere, F., Windheim, M., Ruzsics, Z., Arnberg, N., Adrian, T., Burgert, H.-G. (2002) E3/49K: A novel early region 3 protein specifically expressed by adenoviruses of subgenus D. Virology 296: 94-106.