Paracelsus Medizinische Privatuniversität
Principal Investigator: Prof. Dirk Strunk/ PD Dr. Katharina Schallmoser
Scientists: Patrizia Peking, PhD
Areas of expertise
- Translational cell therapy
- MSC transplantation (for GvHD, multiple sclerosis, vascular disease etc.)
- Clinical bone marrow, mobilized adult peripheral blood and neonatal umbilical cord transplantation
-Platelet biology and diagnostics
- Standard procedures for GMP-compliant large scale animal serum-free human mesenchymal stem cell (MSC) propagation
Main tasks
Work Package 7
- Advancing the processes for primary human MSC expansion:
GMP-grade, animal serum-free and safe propagation of human MSCs from various tissues with superior efficiency adapted to TECHNOBEAT requirements
- Providing fully characterized, animal serum-free MSCs of highest quality for advanced µ-tissue engineering and transplantation
- Elucidating mode of MSC action in conjunction with µ-tissues:
Analyzing protein production, secretion, metabolism and signaling of MSCs with particular focus on hypoxic conditions and on analysis of the secretome derived from µ-tissue cultures
Link: